降钙素原水平在肝硬化腹水合并自发性细菌性腹膜炎诊断中的价值

发布时间：2018-03-25 12:05

本文选题：降钙素原　切入点：肝硬化　出处：《中国老年学杂志》2017年08期

【摘要】：目的探讨检测血清和腹水降钙素原(PCT)在肝硬化合并自发性细菌性腹膜炎(SBP)诊断中的价值。方法选取肝硬化腹水患者102例,按感染情况分为3组:合并SBP 45例(SBP组),其他部位感染27例(其他感染组),单纯腹水30例(单纯腹水组)。30例健康体检者为正常对照组。所有患者于入院抗感染治疗前抽取静脉血和腹水分别检测血清和腹水PCT水平,正常对照组抽取静脉血检测血清PCT水平。结果血清PCT水平比较:SBP组比单纯腹水组、正常对照组均明显升高(P0.05);其他感染组比单纯腹水组明显升高(P0.05);SBP组与其他感染组比较差异不显著(P0.05);单纯腹水组与正常对照组比较差异不显著(P0.05)。腹水比较:SBP组比其他感染组、单纯腹水组均明显升高(P0.05);其他感染组与单纯腹水组比较差异不显著(P0.05)。腹水与血清PCT水平比较:SBP组腹水PCT明显高于血清PCT(P0.05);其他感染组腹水PCT明显低于血清PCT(P0.05);单纯腹水组二者差异不显著(P0.05)。结论血清及腹水PCT相结合可作为肝硬化合并SBP的早期诊断依据。
[Abstract]:Objective to investigate the diagnostic value of serum and ascites procalcitonin (PCT) in the diagnosis of cirrhosis with spontaneous bacterial peritonitis. According to the infection condition, the patients were divided into three groups: 45 cases with SBP, 27 cases with other infection (other infection group, 30 cases with simple ascites). The levels of PCT in serum and ascites were measured before treatment with venous blood and ascites. In normal control group, venous blood was taken to detect the serum PCT level. Results the serum PCT level was higher in the control group than in the ascites group. In the normal control group, the levels of P0.05A were significantly higher in the control group than in the simple ascites group, and there was no significant difference between the other infection group and the other infection group, but there was no significant difference between the pure ascites group and the normal control group (P 0.05). The ascites group was significantly higher than the other infection group in the ascites group, and in the control group, there was no significant difference in the ascites group compared with the other infection groups. The levels of PCT in ascites and serum PCT in ascites were significantly higher than those in serum, and the PCT in other infected groups was significantly lower than that in serum, and the level of PCT in ascites and serum was significantly lower than that in other infected groups. The level of PCT in ascitic fluid was significantly higher than that in the control group (P < 0.05), but the level of PCT in ascites was significantly higher than that in serum (P 0.05); in other infected groups, it was significantly lower than that in serum (P 0.05). Conclusion the combination of serum and ascites PCT can be used as an early diagnostic basis for cirrhosis with SBP.
【作者单位】：中山大学孙逸仙纪念医院预防保健科;中山大学孙逸仙纪念医院消化内科;中山大学孙逸仙纪念医院感染办公室;中山大学孙逸仙纪念医院药剂科;
【分类号】：R575.2;R572.2

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