黑龙江省健康人群乙型病毒性肝炎血清流行病学分析

发布时间：2018-03-28 01:20

本文选题：乙型病毒性肝炎　切入点：血清流行病学调查　出处：《中国公共卫生》2017年10期

【摘要】：目的了解黑龙江省1~29岁人群乙型肝炎(乙肝)病毒(HBV)感染状况和乙肝疫苗(Hep B)预防接种效果,以及乙肝病毒感染者血清标志物8年后的变化情况。方法 2014年9月,在黑龙江省采用分层二阶段整群随机抽样方法,调查7个县(区)932名1~29岁居民,同时对2006年在黑龙江省健康人群乙肝血清学调查中检测出乙肝感染者45人,分别于2009年和2014年追踪调查乙肝病毒感染血清标志物变化情况,应用酶联免疫吸附试验检测乙肝病毒感染血清标志物。结果黑龙江省1~29岁人群HBV感染率为7.51%,乙肝病毒表面抗原(HBs Ag)阳性率为1.29%;Hep B接种率为88.09%。5岁以下人群HBV感染率为3.17%,HBs Ag阳性率为0.26%;Hep B接种率为100%。2006—2014年8年,有66.67%的HBe Ag阳性患者转为HBe Ag阴性。结论黑龙江省1~29岁人群HBs Ag流行率呈下降趋势,黑龙江省乙肝防控工作已显成效。
[Abstract]:Objective to investigate the status of hepatitis B virus (HBV) infection and the preventive effect of hepatitis B vaccine against hepatitis B virus (Hep B) among the 29 year old population in Heilongjiang Province, and the changes of serum markers of hepatitis B virus infection after 8 years. A stratified two-stage cluster random sampling method was used to investigate 932 residents aged 1 to 29 years old in 7 counties (districts) in Heilongjiang Province. Meanwhile, 45 hepatitis B infected persons were detected in the healthy population of Heilongjiang Province in 2006. The changes of serum markers of hepatitis B virus infection were tracked in 2009 and 2014, respectively. Results the infection rate of HBV was 7.51, and the positive rate of hepatitis B antigen was 1.29. The rate of hepatitis B infection was 88.09.5 years old in the population under the age of 88.09.5 in Heilongjiang Province. The positive rate of HBs Ag was 0.26 and the vaccination rate of Hep B was 100. 66.67% of HBe Ag positive patients turned to HBe Ag negative. Conclusion the prevalence rate of HBs Ag in the population aged 1 to 29 years old in Heilongjiang Province showed a downward trend, and the prevention and control work of hepatitis B in Heilongjiang Province has achieved remarkable results.
【作者单位】：黑龙江省疾病预防控制中心免疫规划所;
【分类号】：R181.3;R512.62

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