重症急性胰腺炎多重耐药菌铜绿假单胞菌感染的危险因素分析

发布时间：2018-04-15 10:25

  本文选题：重症急性胰腺炎 + 铜绿假单胞菌　； 参考：《中国现代医学杂志》2017年12期

【摘要】：目的探讨重症急性胰腺炎(SAP)患者并发多重耐药性铜绿假单胞菌(PAE)感染的危险因素及其耐药性分析。方法回顾性纳入该院2006年1月-2016年12月收治的SAP患者102例。根据是否合并多重耐药性PAE感染分为感染组(17例)和对照组(85例),分析两组患者一般情况,采用Logistic回归分析患者感染多重耐药性PAE的危险因素。结果 SAP合并多重耐药性PAE感染的比例为16.67%。两组患者性别、病因及合并疾病发生率比较,差异无统计学意义(P0.05)。感染组年龄、CT危重度评分(CTSI)及SAP危重度分级高于对照组(P0.05);急性期急性呼吸窘迫综合征(ARDS)和休克发生率高于对照组(P0.05);入院时急性生理功能和慢性健康状况评分Ⅱ(APACHEⅡ)评分更高;急性期重症监护病房(ICU)住院天数更长。多因素Logistic回归分析发现,PAE感染的危险因素包括CTSI、SAP危重度、急性期出现ARDS、入院APACHEⅡ评分过高及急性期过长的ICU暴露时间(P0.05)。临床预后方面,相比于对照组,感染组感染期休克和脓毒症发生率高于对照组;ICU住院天数和总住院天数高于对照组,但两组死亡率比较差异无统计学意义。结论 SAP患者PAE感染的危险因素包括CTSI、SAP危重度、急性期ARDS、过长的ICU暴露时间及入院APACHEⅡ评分过高。
[Abstract]:Objective to investigate the risk factors and drug resistance of multidrug resistant Pseudomonas aeruginosa (PAE) infection in patients with severe acute pancreatitis (SAP).Methods 102 cases of SAP were retrospectively included in our hospital from January 2006 to December 2016.According to whether the patients were complicated with multidrug resistant PAE infection, they were divided into two groups: infection group (n = 17) and control group (n = 85). The general conditions of the two groups were analyzed, and the risk factors of infection with multidrug resistance PAE were analyzed by Logistic regression analysis.Results the proportion of SAP complicated with multidrug resistant PAE infection was 16.67%.There was no significant difference in sex, etiology and incidence of complicated diseases between the two groups (P 0.05).The scores of CTSI and SAP in the infection group were higher than those in the control group (P 0.05), the incidence of acute respiratory distress syndrome (ARDS) and shock were higher than those in the control group (P 0.05), and the scores of acute physiological function and chronic health status 鈪，

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