胃食管反流病与牙周病相关性研究

发布时间：2018-04-17 06:18

本文选题：胃食管反流病 + 牙周疾病　；参考：《新疆医科大学》2017年硕士论文

【摘要】：目的:探讨胃食管反流病(Gastroesophageal reflux disease,GERD)的流行病学特点及与牙周疾病的之间的关系及相关危险因素,为其临床预防及治疗提供依据。方法:对于2015年4月到2016年4月就诊于我院的80名GERD患者和71名正常人进行GERD相关问卷和牙周疾病检查,牙周检查以社区牙周指数(Community periodontal index,CPI)和附着丧失(Attachment loss,AL)作为诊断标准,进行单因素分析和多因素Logistic回归分析。结果:GERD患者与对照组比较,年龄,性别,吸烟比列等指标之间差异无统计学意义(P0.05),而民族,BMI指数,等指标之间有统计学差异(P0.05),GERD患者中维吾尔族患者发生牙周疾病比汉族患者多,(Body Mass Index,,BMI)BMI指数、GERD患者牙周炎患病率、在GERD患者中牙周炎严重程度均显著高于对照组,通过Logistics回归分析可知年龄是牙周炎的危险因素,非GERD是牙周疾病的保护因素。结论:可以认为与吸烟,年龄等相关危险因素一样,GERD疾病是牙周疾病的危险因素之一,其诊治需要多科的共同协作,早期诊断胃食管反流病并通过改变生活方式和药物来抑制酸反流,对预防牙周疾病极为重要。口腔以及胃肠都是人体消化系统当中的组成部分,在临床上针对上述两种疾病开展治疗以及预后的时候,都会综合两者间的影响,通过综合考虑能够更好的制定出科学的治疗方法,因此在疾病发生当中有着一定的关联性,但是这一猜测还需要更深入的研究和证实。
[Abstract]:Objective: to investigate the epidemiological characteristics of gastroesophageal reflux disease (GERD) and the relationship between GERD and periodontal disease, and to provide evidence for its clinical prevention and treatment.Methods: from April 2015 to April 2016, 80 patients with GERD and 71 normal controls were examined with GERD related questionnaire and periodontal disease. The periodontal examination was based on the community periodontal index (CPI) and attachment loss (attachment).Univariate analysis and multivariate Logistic regression analysis were performed.Results compared with the control group, there was no significant difference in age, sex and smoking ratio between the two groups, but there was no significant difference in BMI index between the two groups.There was statistical difference between the two indexes. The prevalence of periodontitis in Uygur patients was higher than that in Han patients, and the severity of periodontitis in GERD patients was significantly higher than that in the control group, and the prevalence of periodontitis was significantly higher in Uygur patients than in the Han nationality patients, and the prevalence of periodontitis in the patients with GERD was significantly higher than that in the controls.Age was the risk factor of periodontitis and non-GERD was the protective factor of periodontal disease by Logistics regression analysis.Conclusion: GERD is one of the risk factors of periodontal disease, and the diagnosis and treatment of GERD need the cooperation of many departments.Early diagnosis of gastroesophageal reflux disease and inhibition of acid reflux by changing lifestyle and drugs are very important to prevent periodontal disease.The oral cavity and the gastrointestinal tract are part of the human digestive system, and the clinical treatment and prognosis of these two diseases will combine the effects of the two.Scientific treatment methods can be better formulated through comprehensive consideration, so there is a certain correlation in the occurrence of disease, but this speculation still needs to be further studied and confirmed.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R571

【参考文献】