半夏厚朴汤加味联合西药治疗反流性食管炎（气郁痰阻型）临床疗效观察

发布时间：2018-05-02 07:00

本文选题：半夏厚朴汤 + 中西医联合治疗　；参考：《成都中医药大学》2015年硕士论文

【摘要】：目的：观察半夏厚朴汤加味+兰索拉唑片、枸橼酸莫沙必利分散片联合治疗反流性食管炎(气郁痰阻型)临床疗效。方法：研究对象为2014年1月—2014年12月就诊于成都中医药大学附属医院消化内科门诊病人,符合纳入及排除标准患者60例,随机(抽签法)分为两组,其中中西医组30例,给予中药半夏厚朴汤加味+兰索拉唑片、枸橼酸莫沙必利分散片。西医组30例,给予兰索拉唑片+枸橼酸莫沙必利分散片。治疗周期均为8周。观察两组患者中医证候评分、RDQ评分及胃镜下食管黏膜的修复情况。记录结果的数据用SPSS 17.0统计软件进行统计学分析。结果：治疗前两组患者的性别、年龄、病程、以及胃镜下食管黏膜的情况等数据比较P0.05。治疗后复查胃镜,中西医组治愈率为27%,总有效率达90%,西医组治愈率为10%,总有效率为87%,二者比较P0.05。中医证候疗效比较,治疗4周时,中西医组总有效率为80%,西医组总有效率为70%,P0.05；治疗8周,中西医组总有效率为97%,西医组总有效率为87%, P0.05。中医证候总积分比较,P0.05。RDQ评分比较：治疗前两组比较P0.05。4周时,中西医组治疗前后RDQ评分比较P0.05；西医组治疗前后RD)Q评分比较P0.05；但两组比较P0.05。8周时,中西医组治疗前后RDQ评分比较P0.01,西医组治疗前后比较P0.05,治疗后两组RDQ评分比较P0.05。结论：中西医联合治疗反流性食管炎(气郁痰阻型)比纯西医治疗更具有优势,并且安全有效,可以在辨证论治的基础上在临床推广应用,有进一步深入研究的价值。
[Abstract]:Objective: to observe the clinical effect of Banxia Houpu decoction lansoprazole tablet and mosapride citrate dispersible tablet in the treatment of reflux esophagitis. Methods: from January 2014 to December 2014, 60 outpatients in the Department of Digestive Medicine, affiliated Hospital of Chengdu University of traditional Chinese Medicine, were randomly divided into two groups, including 30 cases in Chinese and western medicine group, 30 cases in traditional Chinese and western medicine group, and 60 cases in accordance with the criteria of inclusion and exclusion. Banxia Houpu decoction lansoprazole tablet, mosapride citrate dispersible tablets. In the western medicine group, 30 cases were treated with lansoprazole tablets and mosapride citrate dispersible tablets. The treatment cycle was 8 weeks. The RDQ score of TCM syndromes and the repair of esophageal mucosa under gastroscope were observed. The data recorded were analyzed by SPSS 17.0 statistical software. Results: the data of sex, age, course of disease, and the condition of esophagus mucosa under gastroscopy were compared between the two groups before treatment (P 0.05). After reexamination of gastroscope, the cure rate of TCM and Western medicine group was 27, the total effective rate was 90, the cure rate of western medicine group was 10, the total effective rate was 87, the comparison between them was P0.05. After 4 weeks of treatment, the total effective rate of traditional Chinese and western medicine group was 80 and the total effective rate of western medicine group was 70 P0.05; after 8 weeks treatment, the total effective rate of traditional Chinese and western medicine group was 97%, and the total effective rate of western medicine group was 87 and P 0.05 respectively. Comparison of the total score of TCM syndromes and P0.05.RDQ score: before and after treatment, the RDQ score of the two groups was compared with that of the control group (P0.05); the RD)Q score of the western medicine group was compared with that of the control group (P0.05); but the two groups were compared at P0.05.8 weeks. Before and after treatment, the RDQ score of the traditional Chinese and western medicine group was compared with that of the western medicine group (P0.05), and the RDQ score of the two groups was compared after the treatment (P0.05). Conclusion: the treatment of reflux esophagitis (Qi stagnation and phlegm obstruction type) with combination of traditional Chinese and Western medicine has more advantages than that of pure western medicine, and it is safe and effective. It can be popularized and applied in clinic on the basis of syndrome differentiation and has the value of further study.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R571

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