慢性乙型肝炎合并焦虑症患者生存质量及免疫指标的变化研究

发布时间：2018-05-09 00:39

本文选题：慢性乙型肝炎 + 焦虑症　；参考：《中华医院感染学杂志》2017年04期

【摘要】：目的分析慢性乙型肝炎合并焦虑症患者生存质量及免疫指标的变化情况,为患者的诊断与治疗提供依据。方法选取2014年1月-2015年11月于医院进行治疗的慢性乙型肝炎合并焦虑症患者48例为观察组,慢性乙型肝炎患者48例为对照组,将对照组和观察组生存质量及红细胞免疫、细胞免疫指标进行比较,同时比较观察组轻度、中度及重度焦虑症患者的生存质量及红细胞免疫、细胞免疫指标。结果观察组生存质量方面包括生理方面、心理方面、社会关系及环境领域的评分分别为(52.21±5.40)分、(54.22±5.61)分、(50.17±4.82)分及(58.81±5.80)分,其低于对照组(61.32±5.79)分、(65.42±6.13)分、(60.28±5.46)分及(70.64±6.57)分,观察组红细胞免疫及细胞免疫指标也均差于对照组,且观察组轻度、中度及重度焦虑症患者的生存质量及红细胞免疫、细胞免疫指标也存在明显差异,差异有统计学意义(P0.05)。结论慢性乙型肝炎合并焦虑症患者生存质量及免疫指标相对较差,且焦虑程度对其评估结果也有较大影响,因此应重视慢性乙型肝炎患者焦虑症的治疗。
[Abstract]:Objective to analyze the changes of quality of life (QOL) and immune index in patients with chronic hepatitis B (CHB) complicated with anxiety disorder, and to provide evidence for diagnosis and treatment. Methods from January 2014 to November 2015, 48 patients with chronic hepatitis B complicated with anxiety disorder were selected as observation group and 48 patients with chronic hepatitis B as control group. The quality of life, erythrocyte immunity and cellular immunity of patients with mild, moderate and severe anxiety disorder were compared. Results the scores of quality of life in the observation group were 52.21 卤5.40), 54.22 卤5.61) and 58.81 卤5.80, respectively, which were lower than those in the control group (65.42 卤5.79), 60.28 卤5.46) and 70.64 卤6.57 respectively, and the scores in the observation group were 52.21 卤5.40), 50.17 卤4.82) and 58.81 卤5.80 respectively, which were lower than those in the control group (65.42 卤5.79), 60.28 卤5.46) and 70.64 卤6.57, respectively. The mean of erythrocyte immunity and cellular immunity in the observation group was also lower than that in the control group, and there were significant differences in the quality of life, erythrocyte immunity and cellular immunity in the patients with mild, moderate and severe anxiety disorder in the observation group, and the difference was statistically significant (P 0.05). Conclusion the quality of life and immune index of patients with chronic hepatitis B and anxiety disorder are relatively poor, and the degree of anxiety has great influence on the evaluation results. Therefore, the treatment of anxiety disorder in patients with chronic hepatitis B should be paid more attention to.
【作者单位】：杭州市第七人民医院十五病房;温州医科大学附属第二医院脑外科;
【基金】：浙江省医药卫生科技计划项目(2010C33090)
【分类号】：R512.62;R749.72

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