肝硬化患者医院感染率及危险因素

发布时间：2018-05-09 15:22

本文选题：肝硬化 + 医院感染　；参考：《中国感染控制杂志》2015年05期

【摘要】：目的探讨肝硬化患者医院感染的特点及相关危险因素,以制定有效的策略,预防和减少医院感染的发生。方法收集某院2013年1—12月507例肝硬化住院患者的临床资料,对其医院感染现状,病原菌构成及危险因素进行分析。结果507例肝硬化患者中,48例发生医院感染,感染率为9.47%,感染部位主要以腹腔(31.25%)为主;细菌培养送检标本48份,送检率100.00%;共检出病原菌43株,其中革兰阴性(G-)菌25株(58.14%)、革兰阳性(G+)菌10株(23.26%)、真菌8株(18.60%)。危险因素单因素分析结果显示,不同年龄、住院时间、白细胞计数、清蛋白水平、肝功能分级、有无侵入性操作、有无并发症及是否预防性使用抗菌药物的肝硬化患者医院感染发生率比较,差异均有统计学意义(均P0.05)。结论肝硬化患者医院感染率较高,引起感染危险因素较多,应根据危险因素制定相应的干预措施,以减少肝硬化患者医院感染的发生。
[Abstract]:Objective to investigate the characteristics and risk factors of nosocomial infection in cirrhotic patients and to establish effective strategies to prevent and reduce nosocomial infection. Methods the clinical data of 507 inpatients with liver cirrhosis from January to December 2013 were collected, and the nosocomial infection status, pathogenic bacteria composition and risk factors were analyzed. Results Nosocomial infection occurred in 48 of 507 patients with liver cirrhosis, the infection rate was 9.477.The main site of infection was abdominal cavity 31.25.The bacterial culture was carried out in 48 samples, the rate was 100.000.43 strains of pathogenic bacteria were detected. Among them, 25 strains of Gram-negative G) were found to be 58.14%, 10 strains of Gram-positive G) were found to be 23. 26% and 8 strains of fungi were 18. 60%. Univariate analysis of risk factors showed that age, length of stay in hospital, white blood cell count, albumin level, liver function grade, invasive operation or not, The incidence of nosocomial infection in cirrhotic patients with or without complications and prophylactic use of antimicrobial agents was statistically significant (P 0.05). Conclusion the nosocomial infection rate of patients with liver cirrhosis is higher and the risk factors of infection are more. The corresponding intervention measures should be made according to the risk factors in order to reduce the incidence of nosocomial infection in patients with liver cirrhosis.
【作者单位】：苏州市第五人民医院;
【分类号】：R575.2

【参考文献】