早期血液滤过对重症急性胰腺炎合并腹腔间隔室综合征的影响

发布时间：2018-05-10 11:33

本文选题：重症急性胰腺炎 + 腹腔间隔室综合征　；参考：《中国现代医学杂志》2017年23期

【摘要】：目的研究早期血液滤过对重症急性胰腺炎(SAP)合并腹腔间隔室综合征(ACS)患者各脏器功能及腹内压的影响。方法选取SAP合并ACS患者48例,其中37例(治疗组)除在ICU进行常规治疗外,同时进行血液滤过治疗;其余11例(对照组)因经济困难等原因未行血液滤过和手术治疗,只行常规治疗。治疗期间观察并记录两组患者的症状、体征及不良反应。于治疗前和治疗后1~6 d检测患者血尿淀粉酶、肝肾功能及C反应蛋白(CRP),同时测定患者的腹内压。结果治疗组患者症状体征消失时间、住院时间较对照组缩短(P0.05)。治疗组治疗后1~6 d患者血尿淀粉酶、肝肾功能、CRP及腹内压低于对照组(P0.05)。结论早期血液滤过能有效降低SAP合并ACS患者的腹内压,改善症状,促进肝肾功能尽快恢复,避免多脏器功能衰竭,降低死亡率。
[Abstract]:Objective to study the effects of early hemofiltration on organ function and abdominal pressure in patients with severe acute pancreatitis (SAP) complicated with abdominal septal syndrome (ACSS). Methods Forty-eight patients with SAP and ACS were selected, 37 of them (treatment group) were treated with hemofiltration in addition to routine treatment in ICU, the other 11 cases (control group) were not treated with hemofiltration or surgical treatment due to economic difficulties. Only routine treatment was performed. Symptoms, signs and adverse reactions were observed and recorded during treatment. The serum amylase, liver and kidney function and C-reactive protein (CRP) were measured before and 6 days after treatment, and the intraabdominal pressure of the patients was measured at the same time. Results the time of disappearance of symptoms and signs in the treatment group was shorter than that in the control group (P 0.05). In the treatment group, the levels of serum amylase, CRP of liver and kidney function and intraabdominal depression were significantly lower than those of the control group on the 6th day after treatment. Conclusion early hemofiltration can effectively reduce the abdominal pressure, improve symptoms, promote the recovery of liver and kidney function, avoid multiple organ failure and reduce mortality in SAP patients with ACS.
【作者单位】：潍坊医学院附属益都中心医院消化内科;山东省青州荣军医院消化内科;
【分类号】：R576

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