甲胎蛋白对慢性HBV感染后重型肝炎预后的预测价值
发布时间:2018-05-11 10:06
本文选题:甲胎蛋白 + 乙型肝炎病毒 ; 参考:《广东医学》2015年05期
【摘要】:目的探讨慢性乙型肝炎病毒(HBV)感染后重型肝炎患者血清甲胎蛋白(AFP)值的变化与MELD评分对其预后的评估效果。方法选择慢性HBV感染后重型肝炎患者82例,检测其血清AFP并对其进行MELD评分,随访90 d并比较血清AFP值与MELD评分对预后的评估效果。结果 MELD≤19分的患者存活率高于MELD≥20分的患者,差异有统计学意义(P0.05),而AFP200μg/L的患者存活率高于AFP200μg/L者,差异有统计学意义(P0.05),MELD评分分级和AFP分级与患者的存活率有关(P0.05)。结论 AFP对慢性HBV感染后重型肝炎预后判断有较好的应用价值。
[Abstract]:Objective to investigate the changes of serum alpha-fetoprotein (AFP) in patients with severe hepatitis B after chronic hepatitis B virus (HBV) infection and the effect of MELD score on prognosis. Methods 82 patients with severe hepatitis after chronic HBV infection were selected, their serum AFP was measured and their MELD scores were evaluated. After 90 days follow-up, the prognosis of patients with severe hepatitis after chronic HBV infection was compared with that of serum AFP score and MELD score. Results the survival rate of patients with MELD 鈮,
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