维持性血液透析肝病患者感染的临床研究

发布时间：2018-05-14 04:28

本文选题：维持性血液透析 + 肝病　；参考：《中华医院感染学杂志》2015年10期

【摘要】：目的了解维持性血液透析肝病患者发生感染情况,分析发生感染的因素,总结有效的防治措施,以降低临床感染率。方法选取1998年5月-2014年12月医院行维持性血液透析的肝病患者67例,采用回顾性调查方法对感染患者的年龄、感染部位分布及基础疾病等进行分析,使用SPSS15.0软件进行统计分析。结果 67例患者中42例发生感染,感染率62.69%,其中患有慢性肾小球肾炎、糖尿病肾病、移植肾失功、多囊肾患者的感染率分别为57.50%、66.67%、100.00%、0;患有慢性乙型肝炎、慢性丙型肝炎、肝硬化患者的感染率分别为61.82%、66.67%、77.78%;感染部位以上呼吸道感染为主,占50.00%,其次为肺部感染和肠道感染,分别占38.10%和7.14%;感染患者以51~60岁最多,占52.38%,其次为61~70岁和41~50岁,分别占21.43%和14.29%;透析时间越长、肝功能越差,感染率越高。结论维持性血液透析合并肝脏疾病患者感染率较高,应加强基础疾病的治疗,增强机体抵抗力,规范操作流程,合理应用抗菌药物,以减少感染的发生。
[Abstract]:Objective to investigate the incidence of infection in patients with maintenance hemodialysis liver disease, analyze the factors of infection, and summarize the effective prevention and treatment measures to reduce the clinical infection rate. Methods Sixty-seven patients with liver diseases undergoing maintenance hemodialysis from May 1998 to December 2014 were selected. The age, distribution and underlying diseases of infected patients were analyzed by retrospective investigation. SPSS15.0 software was used for statistical analysis. Results the infection rate was 62.69% in 42 of 67 patients with chronic glomerulonephritis, diabetic nephropathy, kidney allograft dysfunction and polycystic kidney failure. The infection rates of the patients with polycystic kidney were 57.50% and 66.67% respectively, and those with chronic hepatitis B and chronic hepatitis C were 57.50%, 66.67% and 100.000 respectively. The infection rate in patients with liver cirrhosis was 61.82 and 66.677.78.The infection site was mainly upper respiratory tract infection (50.00), followed by pulmonary infection (38.10%) and intestinal infection (7.14%). The longer the dialysis time, the worse the liver function and the higher the infection rate. Conclusion the infection rate of maintenance hemodialysis patients with liver diseases is high. It is necessary to strengthen the treatment of basic diseases, strengthen the body resistance, standardize the operation procedure, and use antibiotics rationally to reduce the incidence of infection.
【作者单位】：首都医科大学附属北京佑安医院泌尿中心;
【基金】：北京市科学技术委员会国家科技合作基金资助项目(2012DFA31240)
【分类号】：R575

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