血液灌流联合连续性静脉-静脉血液滤过治疗高脂血症性胰腺炎的疗效
发布时间:2018-05-22 19:12
本文选题:高脂血症性胰腺炎(HLP) + 血液灌流(HP) ; 参考:《中国老年学杂志》2015年18期
【摘要】:目的探讨血液灌流(HP)联合连续性静脉-静脉血液滤过(CVVH)技术治疗高脂血症性胰腺炎(HLP)的临床疗效。方法将19例HLP患者随机分为两组,联合治疗组10例采用HP+CVVH治疗,对照组9例采用常规CVVH治疗,比较两组治疗前后甘油三酯(TG);肿瘤坏死因子(TNF)-α、白介素(IL)-1、IL-6等细胞因子水平及急性生理与慢性健康评分(APACHE)Ⅱ和存活率。结果联合治疗组治疗7 d后TG、TNF-α、IL-1、IL-6及APACHEⅡ评分均呈下降趋势,与对照组比较差异显著(P0.05);联合治疗组存活率7/10(70%)明显高于对照组5/9(55.6%)。结论 HP联合CVVH治疗能迅速降低血脂,有效调整炎症因子水平,改善HLP患者预后,提高存活率。
[Abstract]:Objective to investigate the clinical effect of hemoperfusion combined with continuous veno-venous hemofiltration (CVVH) in the treatment of hyperlipidemic pancreatitis. Methods 19 patients with HLP were randomly divided into two groups. The combined treatment group (n = 10) was treated with HP CVVH and the control group (n = 9) with conventional CVVH. The levels of triglyceride, TNF- 伪, interleukin-1 (IL-1) IL-6, acute physiological and chronic health scores (Apache 鈪,
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