血必净注射液辅助治疗急性重症胰腺炎的疗效观察

发布时间：2018-05-23 09:55

本文选题：血必净注射液 + 急性重症胰腺炎　；参考：《中国药房》2015年32期

【摘要】：目的:观察血必净注射液辅助治疗急性重症胰腺炎的疗效。方法:选择急性重症胰腺炎患者80例,按随机数字表法分为对照组和观察组,各40例。对照组患者采用对症支持处理,观察组患者在对照组的基础上加用血必净注射液静脉滴注,每次100ml,每天2次。比较治疗前后两组患者肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)和超敏C反应蛋白(hs-CRP)的水平,以及器官衰竭情况。结果:治疗前两组患者TNF-α、IL-6和hs-CRP水平差异无统计学意义(P0.05);治疗后观察组患者的TNF-α、IL-6和hs-CRP水平均显著低于对照组及治疗前,差异均有统计学意义(P0.05)。观察组患者发生肾功能、呼吸功能与循环功能衰竭的比例均显著低于对照组,差异有统计学意义(P0.05)。结论:急性重症胰腺炎患者在对症治疗中加用血必净注射液能显著降低机体炎症水平,减少对器官功能的损伤。
[Abstract]:Objective: to observe the efficacy of Xuebijing injection in the treatment of severe acute pancreatitis. Methods: 80 patients with severe acute pancreatitis were randomly divided into control group (n = 40) and observation group (n = 40). The patients in the control group were treated with symptomatic support, and the patients in the observation group were treated with Xuebijing injection, 100 ml per time, twice a day, on the basis of the control group. The levels of TNF- 伪, IL-6 and hs-CRP, and organ failure were compared between the two groups before and after treatment. Results: there was no significant difference in the levels of TNF- 伪 IL-6 and hs-CRP between the two groups before and after treatment, but the levels of TNF- 伪 -IL-6 and hs-CRP in the observation group were significantly lower than those in the control group and before treatment (P 0.05). The ratio of renal function, respiratory function and circulatory failure in the observation group was significantly lower than that in the control group (P 0.05). Conclusion: Xuebijing injection can significantly reduce the level of inflammation and damage to organ function in patients with severe acute pancreatitis.
【作者单位】：武警后勤学院附属医院;
【分类号】：R576

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