肝脏门静脉期双能CT:单能量图像与融合图像的比较

发布时间：2018-06-04 06:12

  本文选题：双能CT + 肝脏门静脉期　； 参考：《中国医学计算机成像杂志》2017年02期

【摘要】：目的:探比较双能CT(DECT)的单能量图像和融合图像在肝脏门静脉期增强的应用效果。方法:配置不同浓度碘对比剂溶液制成体模原型,在Siemens SOMATOM Definition Flash扫描仪上,采用上腹部推荐协议先后执行常规120k Vp扫描和100/Sn 140k Vp双能扫描。其中,后者所采集图像数据分别重建得到权重配比为0.5的线性融合图像(M_0.5)、最优非线性融合图像(OCM)和根据对比度噪声比(CNR)能谱曲线优选的单能量图像(Mono)。计算对比度、CNR和品质因数(FOM)以比较图像质量。回顾分析30例上腹部双能CT增强检查,比较门静脉期不同重建图像的肝实质和门静脉主干的增强幅度,并采用6分量表法对最大密度投影(MIP)和容积再现(VR)图像进行主观评价。结果:体模实验中,与120k Vp图像相比,M_0.5图像的对比度无显著差异(P=0.239)但CNR提高16.3%;DECT三种重建图像中,OCM和Mono图像的对比度、CNR分别比M_0.5图像提高33.3%、32.3%和16.6%、6.1%;DECT三种重建图像的FOM比120k Vp图像分别提高10.3%、94.2%和24.5%。临床病例的门静脉期OCM和Mono图像的肝实质和门静脉主干增强幅度比M_0.5图像分别提高20.4%、19.2%和16.2%、15.9%;MIP和VR图像的评分中,OCM组和Mono组无显著差别(P=0.317),均显著高于M_0.5组(P0.001)。结论:在上腹部DECT增强检查中,为提高肝脏门静脉期图像增强效果应重建OCM图像。
[Abstract]:Aim: to compare the application effect of single energy image and fusion image of dual energy CTD ECT in portal vein phase of liver. Methods: the phantom prototype was made with different concentrations of iodine contrast agent solution. The routine 120k VP scan and the 100/Sn 140k VP dual-energy scan were performed on the Siemens SOMATOM Definition Flash scanner using the epigastric recommendation protocol. Among them, the image data collected by the latter can reconstruct respectively the linear fusion image with weighted ratio of 0.5, the optimal nonlinear fusion image OCMM) and the single energy image selected according to the contrast noise ratio (CNR) energy spectrum curve. Contrast CNR and quality factor FOM were calculated to compare image quality. A retrospective analysis of 30 cases of epigastric dual-energy CT enhancement was performed to compare the enhancement of liver parenchyma and portal vein trunk in different reconstructed images of portal vein. The maximum density projection (MIP) and volumetric reconstruction (VRV) images were evaluated by 6 subscales. Results: in the phantom experiment, There was no significant difference in contrast between the two images (P < 0. 239), but CNR increased the contrast of Mono and OCM images in three reconstructed images by 33. 33% and 16. 6% higher than that of M0. 5 respectively. The FOM of the reconstructed images was 10. 3% and 24. 552% higher than that of 120 k VP images, respectively. The liver parenchyma and portal vein trunk enhancement amplitude of OCM and Mono images in portal phase of clinical cases were 20.442% and 16.20.90% higher than those of M0. 5, respectively. There was no significant difference between OCM group and Mono group, both of which were significantly higher than that of M + 0. 5 group (P 0.001). Conclusion: in the DECT enhancement of upper abdomen, OCM should be reconstructed in order to improve the enhancement effect of hepatic portal phase image.
【作者单位】： 第三军医大学西南医院放射科;第三军医大学生物医学工程学院;
【基金】：全军医学科技“十二五”重点课题(BWS11J015)
【分类号】：R575;R816.5
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本文编号：1976306