消化道炎性纤维性息肉14例临床病理分析

发布时间：2018-06-06 05:30

本文选题：炎性纤维性息肉 + 消化道　；参考：《临床与实验病理学杂志》2015年10期

【摘要】：目的探讨消化道炎性纤维性息肉(inflammatory fibroid polyps,IFPs)的临床病理学特征、诊断、鉴别诊断及临床治疗。方法回顾性分析14例消化道IFPs的临床病理学特征并复习相关文献。结果 14例IFPs中大体表现多为黏膜下息肉样或半球形隆起性肿物,光镜下以增生的梭形纤维细胞围绕血管形成"洋葱皮样"外观及间质较多嗜酸性粒细胞浸润为主要组织学特征,免疫组化标记肿瘤细胞表达纤维和肌纤维母细胞及树突细胞表型。结论 IFPs是消化道少见的良性间叶性肿瘤,具有独特的病理组织学改变,手术或内镜下肿物完整切除是主要的治疗方法。
[Abstract]:Objective to investigate the clinicopathological features, diagnosis, differential diagnosis and clinical treatment of inflammatory fibroid polyps (IFPs). Methods the clinicopathological features of 14 cases of digestive tract IFPs were retrospectively analyzed and the related literatures were reviewed. Results in 14 cases of IFPs, most of them were submucous polypoid or hemispherical bulge. Under the light microscope, the proliferative fusiform fibrocells formed the appearance of "onion skin" and the infiltration of eosinophilic granulocytes in the interstitial tissue around the blood vessels as the main histological features. The phenotypes of fibroblasts, myofibroblasts and dendritic cells were labeled by immunohistochemistry. Conclusion IFPs is a rare benign mesenchymal tumor of the digestive tract with unique histopathological changes. Surgery or complete resection of the tumor under endoscope is the main treatment.
【作者单位】：南京军区福州总医院病理科;福州市第八医院病理科;
【分类号】：R57

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