幽门螺杆菌感染对胃溃疡患者胃蛋白酶原及胃肠动力状态的影响研究

发布时间：2018-06-08 23:42

本文选题：幽门螺杆菌感染 + 胃溃疡　；参考：《中华医院感染学杂志》2017年10期

【摘要】：目的探讨幽门螺杆菌感染对胃溃疡患者胃蛋白酶原及胃肠动力状态的影响,为临床诊治提供参考依据。方法选取2015年2月-2016年9月医院收治的56例胃溃疡且幽门螺杆菌阳性患者为A组,同期56例胃溃疡且幽门螺杆菌阴性患者为B组,另选同期56名健康者为C组,比较三组胃蛋白酶原及胃肠动力状态相关指标,同时比较A组不同类型幽门螺杆菌感染患者的检测结果。结果 A组的血清胃蛋白酶原相关指标均低于B组及C组,B组则低于C组,A组胃肠动力状态相关指标均差于B组及C组,B组则差于C组,且A组不同类型幽门螺杆菌感染患者的检测结果也存在显著性差异(P均0.05),检测结果间均有显著性差异。结论幽门螺杆菌感染对胃溃疡患者胃蛋白酶原及胃肠动力状态的不良影响较大,且幽门螺杆菌的类型对其影响也较为明显,因此,应重视对胃溃疡患者进行幽门螺杆菌的监测。
[Abstract]:Objective to investigate the effect of Helicobacter pylori infection on pepsinogen and gastrointestinal motility in patients with gastric ulcer. Methods from February 2015 to September 2016, 56 patients with gastric ulcer and Helicobacter pylori positive were selected as group A, 56 patients with gastric ulcer and negative Helicobacter pylori as group B, and 56 healthy persons as group C. The pepsinogen and gastrointestinal motility were compared among three groups, and the results of different types of Helicobacter pylori infection in group A were compared. Results the serum pepsinogen related indexes in group A were lower than those in group B and group C were lower than those in group C and group A were lower than those in group B and group C, respectively. In group A, there were significant differences in the detection results of different types of Helicobacter pylori infection patients (P < 0.05), and there were significant differences in the results of detection among the patients with different types of Helicobacter pylori infection. Conclusion Helicobacter pylori infection has a great negative effect on pepsinogen and gastrointestinal motility in patients with gastric ulcer, and the type of Helicobacter pylori has a significant effect on it. Therefore, we should pay attention to the monitoring of Helicobacter pylori in patients with gastric ulcer.
【作者单位】：滨州医学院烟台附属医院消化内科;
【基金】：山东省医药卫生科技厅科研基金资助项目(2015WS0501)
【分类号】：R573.1

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