通辽地区门诊患者脂肪肝相关因素调查研究

发布时间：2018-06-16 06:59

  本文选题：门诊 + 通辽地区　； 参考：《内蒙古民族大学》2017年硕士论文

【摘要】：目的:通过本项研究为脂肪肝针对性预防和治疗措施提供科学依据及为蒙医学上存在脂肪肝之病名、治疗方法、治疗药物等方面模糊的问题提供基础资料,尤其对蒙医治疗研究提供有意义的研究资料。方法:对内蒙古民族大学附属医院蒙医消化内科门诊患者及各门诊CT检查通辽地区人群中随机抽取脂肪肝组、非脂肪肝组进行1.流行病学问卷调查2.人体学指标3.辅助检查,建立数据库,进行应用SPSS17.0统计软件分析,两组之间采用x2检验,采用多因素非条件性logistic回归分析。结果:2015年7月至2016年10月调查人数共为14603名,其中彩超诊断9581名,CT检查5022名。脂肪肝组900名,男性487名,女性413名,非脂肪肝组901名,男性487名,女性414名。两组对比结果:男性检出率为50%,女性检出率为49.9%,(X2=4.739,P0.05),≤35岁检出率为44.27%,35岁检出率为50.65%,(X2=2.789,P0.05)。≤60岁检出率为49.38%,60岁检出率为51.93%,(X2=0.913,P0.05)。蒙古族检出率50.13%,汉族检出率49.29%,(X2=0.640,P0.05)。干部检出率46.17%,农民检出率52.14%,退休人员检出率51.29%,(X2=7.079,P0.05)。库伦旗检出率15.7%,科左中旗检出率29.5%,科左后旗检出率15.9%,通辽市检出率7.8%,开鲁县检出率8.7%,奈曼旗检出率8.6%,扎鲁特旗检出率10.9%,科尔沁区检出率2.9%,(X2=7.456,P0.05)。实验室检验:ALT、GGT、AST、TBIL、DBIL、TCHO、TG、LDL-C、血糖(P0.05)。生活习惯:饮酒(X2=48.955,P0.05)、吸烟:不吸烟检出率44.04%,1-10支/日检出率63.8%,11支/日检出率68.7%,(X2=70.265,P0.05)、偏油(X2=677.285,P0.05)、偏蔬菜(X2=0.49,P0.05)、偏水果(X2=0.376,P0.05)、偏咸(X2=763.541,P0.05)、运动:经常运动或重体力劳动检出率28.46%,运动缺乏或轻体力劳动检出率61.05%(X2=186.933,P0.05)。两组对比结果:腰围(P0.05)BMI(P0.05)。多因素非条件性logistic回归分析:下肢浮肿、食欲减退、易出汗、脸面部出油、消化不良、乏力、肥胖、GGT、TG、LDL-C、偏油、偏咸、BMI、运动、环境等因素进入回归方程,表明是脂肪肝的独立危险因素,OR分别为釹28995.125、29.827、19039.044、826.609、2624.177、1689.614、2236.323、1.020、11.714、79.379、6807.615、903.067、5.122、0.095、0.000釺彩超或CT诊断:轻度、中度、重度脂肪肝百分比分别27.6%、0.3%、0.23%或21.8%、0.0%、0.07%。脂肪肝合并胆囊壁毛糙或胆囊壁增厚(胆囊炎)检出率40%。总结:脂肪肝组与非脂肪肝组对比结果示不同性别、年龄、职业、地区、民族的脂肪肝检出率差异无统计学意义,脂肪肝组实验室检验中ALT、GGT、AST、TBIL、DBIL、TCHO、TG、LDL-C、血糖值高于非脂肪肝组,生活习惯方面饮酒、吸烟、偏油、偏咸、运动与脂肪肝关系密切,腰围、BMI值与脂肪肝直接关系,多因素分析下肢浮肿、食欲减退、易出汗、脸面部出油、消化不良、乏力、肥胖、GGT、TG、LDL-C、偏油、偏咸、BMI、运动、气候(环境)等因素是脂肪肝的独立危险因素。彩超或CT诊断结果:轻度脂肪肝占比例高,脂肪肝合并胆囊壁毛糙或胆囊壁增厚检出率高,说明10名脂肪肝中4名合并胆囊炎。研究结果表明上述独立危险因素和蒙医学“精华不消化病”病因契合。
[Abstract]:Objective: to provide a scientific basis for the prevention and treatment of fatty liver and to provide basic information for the fuzzy problems in Mongolian medicine, such as fatty liver disease, treatment and medicine, especially for the research of Mongolian medical treatment. Method: The Affiliated Hospital of Inner Mongolia University for the Nationalities. The fatty liver group was randomly selected from the outpatient department of the digestive department of the digestive department of the Mongolian medicine and the outpatient CT in the Tongliao area. The non fatty liver group was investigated with 1. epidemiological questionnaires and 2. anthropologic indexes 3. auxiliary examination, the database was established, the SPSS17.0 statistical software was applied to the analysis, the two groups were used x2 test, and the multiple factor non conditional logistic regression was used. Results: from July 2015 to October 2016, a total of 14603 people were surveyed, of which 9581 were diagnosed by color Doppler ultrasound, 5022 were examined by CT, 900 in the fatty liver group, 487 in the male, 413 in the female, 901 in the non fatty liver group, 487 in the male and 414 in the female. The results of two groups: the male detection rate was 50%, the female detection rate was 49.9%, (X2=4.739, P0.05), and was less than 35 years. The rate of 44.27% and 35 years old was 50.65%, (X2=2.789, P0.05). The detection rate of 60 years old was 49.38%, the detection rate of 60 years old was 51.93%, (X2=0.913, P0.05). The Mongolian detection rate was 50.13%, the Han detection rate was 49.29%, (X2=0.640, P0.05). The detection rate of cadres was 46.17%, the detection rate of farmers was 52.14%, and the detection rate of retirees (X2=7.079, P0.05). The detection rate of Kulun flag was 15.7%, The detection rate of Ko Zuo Zhongqi was 29.5%, the detection rate of left behind flag was 15.9%, the detection rate of Tongliao city was 7.8%, the detection rate of Kailu County was 8.7%, the detection rate of Naiman Banner was 8.6%, the detection rate of khorat flag was 10.9%, the detection rate of khorqin district was 2.9%, (X2=7.456, P0.05). Laboratory test: ALT, GGT, AST, TBIL, DBIL, TCHO, TG, LDL-C, blood sugar (P0.05). Drinking (X2=48.955, P0.05). Smoke detection rate was 44.04%, 1-10 / day detection rate was 63.8%, 11 / day detection rate was 68.7%, (X2=70.265, P0.05), partial oil (X2=677.285, P0.05), partial vegetables (X2=0.49, P0.05), partial fruit (X2=0.376, P0.05), salty (X2=763.541, P0.05), exercise: regular exercise or heavy manual labor detection rate 28.46%, exercise deficiency or light physical labor detection rate 61.05% (X2) =186.933, P0.05). The two groups of comparison results: the waist circumference (P0.05) BMI (P0.05). Multiple factor non conditional logistic regression analysis: lower extremity edema, anorexia, perspiration, face and face oil, indigestion, fatigue, obesity, GGT, TG, LDL-C, oil, salt, BMI, exercise, environment and other factors into the regression equation, indicating the independent risk factor of fatty liver, OR score points. Do not diagnose neodymium 28995.125,29.82719039.044826.6092624.1771689.6142236.323,1.020,11.714,79.3796807.615903.067,5.122,0.095,0.000 color Doppler ultrasound or CT: mild, moderate, and severe fatty liver percentage 27.6%, 0.3%, 0.23% or 21.8%, 0%, 0.07%. fatty liver with gallbladder wall rough or gallbladder wall thickening (cholecystitis) detection rate 40%. Conclusion: the comparison between the fatty liver group and the non fatty liver group showed that there was no significant difference in the detection rate of fatty liver in different sex, age, occupation, area and ethnic group. In the laboratory test of fatty liver, ALT, GGT, AST, TBIL, DBIL, TCHO, TG, LDL-C were higher than those of non fat liver, drinking, smoking, partial oil, salty, exercise and fatty liver. Closely related, waist circumference, BMI value and fatty liver direct relationship, multiple factors analysis of lower extremity edema, anorexia, perspiration, face and face oil, dyspepsia, fatigue, obesity, GGT, TG, LDL-C, oil, BMI, exercise, climate (environment) and other factors are independent risk factors of fatty liver. Color Doppler or CT diagnosis results: mild fatty liver accounts for a high proportion, fat, fatty liver, fat The detection rate of the liver with the gallbladder wall or the thickening of the gallbladder wall was high, indicating that 4 of the 10 fatty liver were associated with cholecystitis. The results showed that the above independent risk factors were associated with the cause of the "essential indigestion" of the Mongolian medicine.
【学位授予单位】：内蒙古民族大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R575.5
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本文编号：2025813