内镜下套扎联合药物注射治疗肝硬化合并上消化道出血的疗效

发布时间：2018-06-20 02:22

本文选题：内镜下套扎术 + 肝硬化　；参考：《实用医学杂志》2016年12期

【摘要】：目的:探讨内镜下套扎联合药物注射治疗肝硬化合并上消化出血的疗效。方法:随机双盲法将76例肝硬化合并上消化道出血患者分为2组各38例,对照组采取单纯保守方案治疗,实验组则在对照组基础上行内镜下套扎联合药物注射治疗,比较2组止血时间、住院时间、再出血及治疗前后血流动力学等指标。结果:实验组再出血率、发热发生率分别为2.6%、10.5%,较对照组的21.1%、28.9%差异有统计学意义(P0.05)。实验组与对照组在输血量、止血时间、症状改善时间及住院时间方面比较差异有统计学意义(P0.01)。实验组治疗后门静脉血流量、脾静脉血流量均显著少于对照组,差异有统计学意义(P0.05)。结论:内镜下套扎联合药物注射治疗肝硬化合并上消化出血疗效明确,能明显改善患者静脉曲张血流动力学,再出血率低。
[Abstract]:Objective: to evaluate the efficacy of endoscopic ligation combined with drug injection in the treatment of liver cirrhosis with upper digestive hemorrhage. Methods: 76 patients with liver cirrhosis complicated with upper gastrointestinal hemorrhage were randomly divided into two groups, 38 patients in each group. The control group was treated with simple conservative regimen, while the experimental group was treated with endoscopic ligation combined with drug injection on the basis of the control group. The hemostasis time, hospitalization time, rebleeding and hemodynamics before and after treatment were compared between the two groups. Results: the rate of rebleeding and the incidence of fever in the experimental group were 2. 6% and 10. 5% respectively, which were significantly higher than that in the control group (21. 1% and 28. 9%) (P < 0. 05). There were significant differences in blood transfusion volume, hemostasis time, symptom improvement time and hospitalization time between the experimental group and the control group (P 0.01). The portal vein blood flow and splenic vein blood flow in the experimental group were significantly lower than those in the control group (P 0.05). Conclusion: endoscopic ligation combined with drug injection is effective in the treatment of liver cirrhosis complicated with upper digestive hemorrhage. It can improve the hemodynamics of varicose veins and the rate of rebleeding is low.
【作者单位】：广东省徐闻县人民医院内一科;
【分类号】：R575.2;R573.2

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