左氧氟沙星治疗社区中老年幽门螺杆菌阳性慢性萎缩性胃炎的临床疗效

发布时间：2018-06-21 09:20

本文选题：左氧氟沙星 + 健康教育　；参考：《中国老年学杂志》2015年08期

【摘要】：目的探讨左氧氟沙星新三联疗法结合健康教育治疗社区中老年幽门螺杆菌(Hp)阳性慢性萎缩性胃炎的疗效及安全性。方法将符合纳入标准的90例中老年Hp阳性慢性萎缩性胃炎患者随机分为观察组及对照组,每组45例。观察组采用左氧氟沙星新三联疗法治疗,对照组采用标准三联疗法治疗,疗程1 w,此外两组均实行健康教育;治疗后行快速尿素酶试验和14C呼气试验检测,比较两组Hp根除率及不良反应发生率。结果治疗后,观察组、对照组的总根治率分别为91.2%、84.4%,两组间差异无统计学意义(χ2=0.932 1,P=0.334);不良反应发生率分别为6.7%、13.3%,组间差异无统计学意义(χ2=1.038 9,P=0.308)。结论左氧氟沙星新三联疗法结合健康教育可能是一种有效根除Hp的疗法。
[Abstract]:Objective to investigate the efficacy and safety of levofloxacin combined with health education in the treatment of chronic atrophic gastritis with Helicobacter pylori positive in the community. Methods 90 middle and aged patients with HP positive chronic atrophic gastritis were randomly divided into observation group and control group with 45 cases in each group. The observation group was treated with levofloxacin new triple therapy, the control group was treated with standard triple therapy for one week, in addition, the two groups were given health education, followed by rapid urease test and 14C breath test. HP eradication rate and adverse reaction rate were compared between the two groups. Results after treatment, the total radical cure rate of the observation group and the control group were 91.2 / 84.4, respectively. There was no significant difference between the two groups (蠂 ~ (2 +) (蠂 ~ (2) 0.9321 ~ (1) ~ (1) ~ (0.334) (蠂 ~ (2) and the incidence of side effects were 6.7m ~ (13. 3) and there was no significant difference between the two groups (蠂 ~ (2) 0.38 9 (P ~ (0.308). Conclusion levofloxacin combined with health education may be an effective therapy for HP eradication.
【作者单位】：深圳市龙岗区慢性病防治院;
【分类号】：R573.32

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