胃镜引导下联合注射肾上腺素与喷洒超微大黄粉治疗非静脉曲张性上消化道出血的疗效分析

发布时间：2018-06-29 12:25

本文选题：胃镜 + 肾上腺素　；参考：《中国内镜杂志》2015年10期

【摘要】：目的探讨胃镜引导下联合注射肾上腺素与喷洒超微大黄粉治疗非静脉曲张性上消化道出血(NVUGH)的临床疗效。方法选取2012年1月-2014年12月于该院接受治疗的80例非静脉曲张性上消化道出血患者作为研究对象,回顾性分析其临床资料,按治疗方案分为对照组(n=38)和观察组(n=42)。所有患者均给予禁食、补充血容量和抑制胃酸等常规治疗。对照组在胃镜引导下给予肾上腺素注射治疗,观察组则给予胃镜引导下注射肾上腺素联合喷洒超微大黄粉治疗。观察比较两组患者治疗疗效、止血时间、住院时间、再出血率及不良反应发生情况。结果治疗后,观察组的治疗总有效率为97.6%,明显高于对照组78.9%的总有效率,差异具有统计学意义(P0.05)。观察组止血时间与住院时间分别为(1.5±0.5)d与(8.2±3.2)d,均明显短于对照组患者,差异均有统计学意义(均P0.05)。观察组再出血率4.8%,明显低于对照组再出血率23.7%(P0.05)。治疗过程中,两组患者均未发生严重不良反应,观察组不良反应发生率为23.8%,与对照组21.0%的不良反应发生率比较差异无统计学意义(P0.05)。结论胃镜引导下联合注射肾上腺素与喷洒超微大黄粉治疗非静脉曲张性上消化道出血疗效可靠,治疗有效率高,止血时间与住院时间短,再出血率低,且不良反应轻,临床上值得进一步研究。
[Abstract]:Objective to investigate the clinical effect of combined injection of epinephrine and ultrafine rhubarb powder under gastroscopic guidance in the treatment of non-varicose upper gastrointestinal hemorrhage (NVUGH). Methods from January 2012 to December 2014, 80 patients with non-varicose upper gastrointestinal bleeding were selected as the study objects. The clinical data were retrospectively analyzed. The patients were divided into two groups: control group (n = 38) and observation group (n = 42). All patients were given fasting, blood volume supplement and gastric acid suppression routine treatment. The control group was treated with epinephrine injection under gastroscopy, while the observation group was treated with epinephrine injection and ultrafine rhubarb powder spraying under gastroscopic guidance. The curative effect, hemostatic time, hospitalization time, rebleeding rate and adverse reaction were observed and compared between the two groups. Results after treatment, the total effective rate of the observation group was 97.6, which was significantly higher than that of the control group (78.9%). The difference was statistically significant (P0.05). The hemostasis time and hospitalization time in the observation group were (1.5 卤0.5) d and (8.2 卤3.2) d, respectively, which were significantly shorter than those in the control group (P0.05). The rebleeding rate in the observation group was 4.8, which was significantly lower than that in the control group (23. 7%) (P0.05). In the course of treatment, no serious adverse reactions occurred in the two groups, the incidence of adverse reactions in the observation group was 23.8. there was no significant difference between the two groups in the incidence of adverse reactions (P 0.05) compared with 21.0% in the control group (P0.05). Conclusion the combined injection of epinephrine and ultrafine rhubarb powder under gastroscopic guidance is effective and effective in the treatment of non-varicose upper gastrointestinal bleeding. The hemostasis time and hospital stay are short, the rate of rebleeding is low, and the adverse reaction is mild. It is worthy of further study clinically.
【作者单位】：海南省海南农垦总医院儿科;
【分类号】：R573.2

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