重症急性胰腺炎患者腹腔感染病原菌分布与危险因素分析

发布时间：2018-06-30 06:30

本文选题：重症急性胰腺炎 + 病原菌　；参考：《中华医院感染学杂志》2015年23期

【摘要】：目的探讨重症急性胰腺炎(SAP)患者腹腔感染病原菌特点及危险因素,为临床降低重症急性胰腺炎合并感染提供参考依据。方法回顾性分析2010年1月-2014年12月医院收治的84例重症急性胰腺炎患者临床资料,分析腹腔感染患者病原菌分布,采用logistic回归分析感染的危险因素,数据采用SPSS 19.0软件进行统计分析。结果 84例重症急性胰腺炎患者中发生腹腔感染患者33例,感染率为39.29%;共检出60株病原菌,以革兰阴性菌为主,共41株占68.34%;logistic回归分析显示,禁食时间、肠功能障碍时间、机械通气、合并多器官功能障碍综合征、合并低氧血症、胰腺CT显示坏死等因素是重症急性胰腺炎患者发生腹腔感染的独立危险因素(P0.05)。结论重症急性胰腺炎患者并发腹腔感染危险因素较多,需采取相应措施,降低医院感染率。
[Abstract]:Objective to investigate the characteristics and risk factors of celiac infection in patients with severe acute pancreatitis (SAP), and to provide reference for clinical reduction of severe acute pancreatitis complicated with infection. Methods the clinical data of 84 patients with severe acute pancreatitis admitted in our hospital from January 2010 to December 2014 were analyzed retrospectively. The distribution of pathogens in patients with abdominal infection was analyzed. The risk factors of infection were analyzed by logistic regression analysis. The data were analyzed by SPSS 19.0 software. Results among 84 patients with severe acute pancreatitis, 33 patients had abdominal infection, the infection rate was 39.29.The results showed that 60 strains of pathogenic bacteria were detected, mainly Gram-negative bacteria, 41 strains accounted for 68.34 cases, and logistic regression analysis showed that fasting time, time of intestinal dysfunction, time of fasting, and time of intestinal dysfunction. Mechanical ventilation, multiple organ dysfunction syndrome, hypoxemia and pancreatic CT necrosis were independent risk factors for abdominal infection in patients with severe acute pancreatitis (P0.05). Conclusion there are many risk factors of abdominal infection in patients with severe acute pancreatitis, and the corresponding measures should be taken to reduce the nosocomial infection rate.
【作者单位】：南京医科大学附属淮安市第一人民医院消化科;
【基金】：国家自然科学基金资助项目(81070655)
【分类号】：R576

【参考文献】