健胃消食口服液联合莫沙必利治疗餐后不适综合征的疗效观察

发布时间：2018-07-12 17:58

本文选题：餐后不适综合征 + 健胃消食口服液　；参考：《中国全科医学》2015年09期

【摘要】：目的观察健胃消食口服液联合莫沙必利治疗餐后不适综合征(PDS)的临床疗效。方法选取2014年1—6月西安交通大学第二附属医院消化科门诊收治的PDS患者100例,将患者采用随机数字表法及随机数余数分组法分为对照组和治疗组,每组50例。两组患者均在三餐前30 min口服莫沙必利片5 mg,治疗组患者另在餐后口服健胃消食口服液10 ml,2次/d。均治疗2周。观察两组患者治疗前后的消化道症状积分、临床疗效、简明健康状况调查表(SF-36)各维度得分。结果治疗前两组患者消化道症状积分、SF-36各维度得分间差异无统计学意义(P0.05);治疗后,与对照组比较,治疗组消化道症状积分降低,SF-36的社会功能(SF)、情感职能(RE)得分升高(P0.05)。治疗后治疗组的疗效〔显效24例(48%),有效21例(42%),无效5例(10%)〕优于对照组〔显效17例(34%),有效14例(28%),无效19例(38%)〕(P0.05)。结论健胃消食口服液联合莫沙必利治疗PDS的疗效较单用莫沙必利治疗的疗效显著,且能进一步改善患者的消化道症状和生活质量。
[Abstract]:Objective to observe the clinical effect of Jianwei Xiaoshi oral liquid combined with mosapride in the treatment of postprandial discomfort syndrome (PDS). Methods from January to June 2014, 100 PDS patients were selected and divided into two groups: control group (n = 50) and treatment group (n = 50). The patients in both groups were treated with mosapride tablets (5 mg) 30 min before meal, while patients in the treatment group received 10 ml / d of Jianwei Xiaoshi oral liquid 10 ml / d after meal. All patients were treated for 2 weeks. The scores of digestive tract symptoms, clinical efficacy and SF-36 were observed before and after treatment. Results there was no significant difference in the scores of SF-36 and SF-36 between the two groups before treatment (P0.05). After treatment, the scores of social function (SF) and emotional function (RE) in the treatment group were significantly lower than those in the control group (P0.05). After treatment, the curative effect of the treatment group (24 cases (48%), 21 cases (42%), 5 cases (10%) was better than that of the control group (17 cases (34%), 14 cases (28%), 19 cases (38%) (P0.05). Conclusion the therapeutic effect of Jianwei Xiaoshi Oral liquid combined with mosapride on PDS is more significant than that of mosapride alone, and can further improve the digestive tract symptoms and quality of life of the patients.
【作者单位】：西安交通大学第二附属医院消化内科;
【分类号】：R57

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