阿米巴性结肠炎3例临床病理分析并文献复习
发布时间：2018-07-20 09:03
【摘要】：目的探讨阿米巴性结肠炎的临床病理学特征、诊断及鉴别诊断。方法回顾性分析3例阿米巴性结肠炎的临床表现、内镜和组织学特征,并复习文献讨论阿米巴性结肠炎的诊断和鉴别诊断。结果 3例患者均为男性,年龄27~35岁,临床表现以急性感染症状腹痛、腹泻为主。纤维结肠镜下表现为肠黏膜的阶段性糜烂和溃疡,但病变部位不同。例1位于近阑尾孔处和直肠;例2位于横结肠及直肠;例3位于回肠末端和直肠远端近肛门口。镜下3例病变相似,在炎性坏死的肠黏膜面可见成片分布的大滋养体,滋养体内可见核仁,胞质内见吞噬红细胞现象。结论阿米巴性结肠炎是一种独特的感染性肠病,纤维结肠镜下无明显特异性表现,需与其他肠炎,尤其是慢性炎症性肠病相鉴别,病理学检查查见阿米巴滋养体是确定诊断的主要依据。
[Abstract]:Objective to investigate the clinicopathological features, diagnosis and differential diagnosis of amoebic colitis. Methods three cases of amoebic colitis were analyzed retrospectively, including their clinical manifestations, endoscopic and histological features, and the diagnosis and differential diagnosis of amoebic colitis were reviewed. Results all the 3 patients were male, aged 2735 years. The clinical manifestations were acute infection, abdominal pain and diarrhea. Fiberoptic colonoscopy showed periodic erosion and ulceration of intestinal mucosa, but the lesions were different. Case 1 was located near the appendix foramen and rectum; case 2 was located in transverse colon and rectum; case 3 was located at the distal end of ileum and proximal anal orifice of rectum. The pathological changes of 3 cases were similar under microscope. Large trophozoites, nucleolus and erythrocyte phagocytosis were observed in the inflammatory necrotic intestinal mucosa, nucleolus and erythrocyte in the trophoblast. Conclusion amoeba colitis is a unique infectious enteropathy with no specific manifestation under fiberoptic colonoscopy. It should be distinguished from other enteritis, especially chronic inflammatory enteropathy. Pathological examination of amoeba trophozoites is the main basis for diagnosis.
【作者单位】： 东南大学附属中大医院病理科;江苏省中医院病理科;
【分类号】：R531.11
，
本文编号：2133015
[Abstract]:Objective to investigate the clinicopathological features, diagnosis and differential diagnosis of amoebic colitis. Methods three cases of amoebic colitis were analyzed retrospectively, including their clinical manifestations, endoscopic and histological features, and the diagnosis and differential diagnosis of amoebic colitis were reviewed. Results all the 3 patients were male, aged 2735 years. The clinical manifestations were acute infection, abdominal pain and diarrhea. Fiberoptic colonoscopy showed periodic erosion and ulceration of intestinal mucosa, but the lesions were different. Case 1 was located near the appendix foramen and rectum; case 2 was located in transverse colon and rectum; case 3 was located at the distal end of ileum and proximal anal orifice of rectum. The pathological changes of 3 cases were similar under microscope. Large trophozoites, nucleolus and erythrocyte phagocytosis were observed in the inflammatory necrotic intestinal mucosa, nucleolus and erythrocyte in the trophoblast. Conclusion amoeba colitis is a unique infectious enteropathy with no specific manifestation under fiberoptic colonoscopy. It should be distinguished from other enteritis, especially chronic inflammatory enteropathy. Pathological examination of amoeba trophozoites is the main basis for diagnosis.
【作者单位】： 东南大学附属中大医院病理科;江苏省中医院病理科;
【分类号】：R531.11
，
本文编号：2133015
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