肝癌并发症上消化道出血患者的肝脏硬度与肝纤维化的变化分析

发布时间：2018-07-31 07:59

【摘要】：目的:探讨肝癌并发症上消化道出血患者的肝脏硬度与肝纤维化的变化情况与相关性。方法:2010年9月至2014年2月选择在我院进行检查的肝癌患者80例,其中无并发上消化道出血48例(A组),并发上消化道出血32例(B组),两组进行血生化常规、肝脏硬度与肝纤维化的检测,并且进行相关性分析。结果:B组患者的血小板、丙氨酸氨基转移酶、甲胎蛋白值都明显高于A组,而白蛋白值明显低于A组(均P0.05)。A组患者的肝脏硬度为(10.42±4.12)k Pa,而B组为(15.21±4.68)k Pa,B组的肝脏硬度明显高于A组(P0.05)。B组患者的血清HA、LN、C-Ⅳ和PⅢP含量都明显高于A组(P0.05)。Spearman相关分析表明肝脏硬度与血清HA、LN、C-Ⅳ和PⅢP含量都呈明显正向相关性(P0.05)。结论:肝癌并发症上消化道出血患者的肝脏硬度检测能反映血清肝纤维化水平,两者之间具有正向相关性,肝脏硬度可用于肝癌并发症上消化道出血患者的非创伤性诊断,值得临床推广应用。
[Abstract]:Objective: to investigate the relationship between liver hardness and hepatic fibrosis in patients with upper gastrointestinal hemorrhage. Methods: from September 2010 to February 2014, 80 patients with liver cancer were selected for examination in our hospital, including 48 patients without upper gastrointestinal bleeding (group A) and 32 patients with upper gastrointestinal bleeding (group B). The relationship between liver hardness and liver fibrosis was analyzed. Results the levels of platelet, alanine aminotransferase and alpha-fetoprotein in group B were significantly higher than those in group A. However, albumin level was significantly lower than that in group A (P0.05). The liver hardness in group A was (10.42 卤4.12) k Pa, while that in group B was (15.21 卤4.68) kPA. The hardness of liver in group B was significantly higher than that in group A (P0.05) .B and P 鈪，

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