上消化道出血病因及相关因素12年对比分析

发布时间：2018-08-21 20:50

【摘要】：目的：对比分析福建医科大学附属第一医院消化内科近年收治的上消化道出血（UGIH）病例与12年前该疾病的发病情况，，探讨其病因及相关因素关系变化，总结规律，提高对上消化道出血发病特点的认识方法：收集福建医科大学附属第一医院消化内科2009年5月-2013年4月期间825例UGIH住院患者的临床资料与1992年-2001年期间1150例住院的UGIH病例，就其年龄、性别、发病季节及病因分布进行对比分析结果：①与12年前相比，UGIH平均发病年龄约增加了5岁，老年人总发病率上升11.21%；青年组中DU发病率呈下降趋势（P0.01）；中年组中GC、AGML发病下降（均P0.05）；老年组中GU发病率上升（P0.01），GC、AGML发病则下降（均P0.01）。②12年来UGIH患者总体性别比例无显著变化（P0.05），男性发病率均大于女性，其中GU男女性发病均上升（均P0.01），但其男女比值有下降（P0.05）。③UGIH各季节发病不完全相同，但总体都是冬春季发病率大于夏秋季（P0.05）；与12年前相比较，夏季发病率上升（P0.05），冬季发病率下降（P0.05）；春季里CU发病上升（P0.01），GC、AGML则下降（均P㩳0.05）；夏季DU、AGML发病率下降（均P0.05），GU、CU上升（均P0.01）；秋季DU下降（P0.01），GU发病上升（P0.01）；冬季DU发病下降（P0.05），CU上升（P0.01）。④UGIH主要病因仍是以DU、GU、CU、EGV、GC、AGML为多，与12年前相比DU、GC、AGML发病均呈下降趋势（均P0.01），GU、CU、MWS发病则上升（均P0.01）。结论：十二年来，UGIH的病因分布及相关因素的关系发生着较大的变化，与十二年前相比，UGIH发病平均年龄增加，老年人总发病率呈上升趋势。男性发病均大于女性，其中GU发病中，男女性别比例明显下降。夏季发病率上升，冬季发病有所下降。PU仍是UGIH的首要病因，DU、GC、AGML发病均呈下降趋势，GU、CU、MWS发病则有明显上升。
[Abstract]:Objective: to compare and analyze the incidence of upper gastrointestinal hemorrhage (UGIH) in recent years in the Department of Digestive Medicine, the first affiliated Hospital of Fujian Medical University. Methods to improve the understanding of the characteristics of upper gastrointestinal hemorrhage: collect the clinical data of 825 inpatients with UGIH from May 2009 to April 2013, Department of Digestive Medicine, the first affiliated Hospital of Fujian Medical University 1150 inpatients with UGIH, Compared with 12 years ago, the average age of UGIH increased by 5 years, and the total incidence rate of the elderly increased by 11.21 years. The incidence of DU decreased in the young group (P0.01), in the middle-aged group (P0.05), in the elderly group (P0.01), the incidence of GCU in the elderly group decreased (P0.01). There was no significant change in the overall sex ratio of the patients with UGIH in the past 212 years (P0.05), and the incidence rate of the male was higher than that of the female. The incidence of gu increased in both sexes (P0.01), but the ratio of male and female decreased (P0.05) .3The incidence of UGIH was not identical in different seasons, but the incidence rate in winter and spring was higher than that in summer and autumn (P0.05); compared with 12 years ago, the incidence of GU was higher than that in summer and autumn (P0.05). The incidence of CU increased in summer (P0.05), decreased in winter (P0.05), decreased in spring (P0.01), decreased in summer (P0.05), increased (P0.01) in autumn (P0.01). In winter, the incidence of DU decreased (P0.05). 4 the main cause of UGIH was that the main cause of DUGU was still the AGML. Compared with 12 years ago, the incidence of DUGCU AGML decreased (P0.01) and the incidence of GUCUMWS increased (P0.01). Conclusion: in the past 12 years, the etiological factors and the related factors of UGIH have changed greatly. Compared with 12 years ago, the average age of UGIH incidence has increased, and the total incidence rate of the elderly has been on the rise. The incidence rate of males was higher than that of females, and the ratio of males and females decreased significantly in the onset of gu. The incidence of UGIH increased in summer, but decreased in winter. Pu was still the main cause of UGIH.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R573.2

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