慢性胰腺炎病人营养风险筛查和危险因素分析

发布时间：2018-08-30 08:13

【摘要】：目的:探讨慢性胰腺炎(CP)病人营养风险和相关危险因素。方法:应用营养风险筛查2002(NRS 2002)回顾性筛查156例CP病人的营养风险,纳入14项可能影响CP病人营养风险的临床参数,并行单因素和多因素Logistic回归分析。结果:在156例病人中,营养风险病人的比例明显高于营养不良病人(44.9%vs25.6%,χ~2=12.64,P=0.000 4)。单因素分析显示,性别、是否合并糖尿病、内镜下或外科胰腺干预、使用胰酶替代治疗、是否合并焦虑抑郁状态、是否平素进食不充分、是否使用营养支持和3个月以上营养支持等7项因素与营养风险发生相关(P0.01)。多因素回归结果显示,合并焦虑抑郁状态、平素进食不充分、3个月以上营养支持等为CP病人营养风险发生的危险因素。结论:CP病人营养风险高,需早期心理干预、鼓励恰当进食和适时的肠外或肠内营养支持治疗。
[Abstract]:Objective: to investigate the nutritional risk and related risk factors in patients with chronic pancreatitis (CP). Methods: nutritional risk screening 2002 (NRS 2002) was used to screen 156 patients with CP retrospectively. 14 clinical parameters that might affect the nutritional risk of CP patients were included, and univariate and multivariate Logistic regression analysis were performed. Results: the proportion of nutritional risk patients was significantly higher than that of malnutrition patients (44.9% vs 25.6, 蠂 2 + 12.64% P 0.000 4). Univariate analysis showed that sex, diabetes, endoscopic or surgical pancreatic intervention, trypsin replacement therapy, anxiety and depression, and inadequate diet, 7 factors such as nutrition support and nutrition support for more than 3 months were associated with nutritional risk (P0.01). The results of multivariate regression showed that the risk factors of nutritional risk in patients with CP were anxiety and depression, inadequate intake of plain food and nutritional support for more than 3 months. Conclusion the nutritional risk of the patients is high, and early psychological intervention is needed to encourage proper feeding and timely parenteral or enteral nutrition support therapy.
【作者单位】：上海市普陀区人民医院营养科;同济大学附属同济医院消化科;
【分类号】：R576;R459.3

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