ZJU指数筛查对健康体检人群非酒精性脂肪肝患病风险预测的价值评估:一项基于重庆市体检人群的单中心研究

发布时间：2018-09-07 22:23

【摘要】：目的:通过ZJU指数筛查我院30 826例体检人群中非酒精性脂肪肝(nonalcoholic fatty liver disease,NAFLD)的患病率及人群分布特点。方法:对体检人群的人体测量学和生化指标进行分析,计算ZJU指数数值。将研究对象按年龄、性别分组,基于ZJU指数筛查各组体检人群中NAFLD的患病率,比较不同年龄段和性别间患病率的差异。结果:130 826例研究对象中,基于ZJU指数计算所得NAFLD的患病率为34.83%,其中男性患病率显著高于女性患病率(40.53%vs.29.26%,χ~2=431.440,P=0.000);2在男性人群中,NAFLD最低患病率为21.67%,分布于30岁年龄段;最高患病率为49.90%,分布于50~59岁年龄段,总体患病率呈先上升后下降的趋势(P_(trend)=0.000);3在女性体检人群中,NAFLD最低患病率为8.86%,分布于30岁年龄段,最高患病率为58.70%,分布于≥70岁年龄段,总体患病率随着年龄的增长而呈现上升趋势(P_(trend)=0.000)。结论:我院体检人群NAFLD的总体患病率为34.83%。其中,男性人群为40.53%,女性人群为29.26%,且患病趋势随着年龄的增长而升高。
[Abstract]:Objective: to screen the prevalence and distribution of non-alcoholic fatty liver (nonalcoholic fatty liver disease,NAFLD) in 30 826 cases of non-alcoholic fatty liver in our hospital by ZJU index. Methods: the anthropometric and biochemical indexes were analyzed and the ZJU index was calculated. The subjects were divided into groups according to age and sex. The prevalence rate of NAFLD was screened based on ZJU index, and the differences between age and sex were compared. Results the prevalence rate of NAFLD calculated by ZJU index was 34.83, in which the prevalence rate of male was significantly higher than that of female (40.53 vs.29.26, 蠂 2 431.440 P0.000). The lowest prevalence rate of NAFLD in male population was 21.67 and distributed in the age of 30 years. The highest prevalence rate was 49.90, which was distributed in the age group of 50 to 59 years old. The overall prevalence rate increased first and then decreased (P _ (trend) 0.000). The lowest prevalence of NAFLD was 8.86 in the female physical examination population, and the highest prevalence rate was 58.70% in the age group of 30 years old, and it was distributed in the age group of 鈮，

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