急性胰腺炎病因与局部并发症及严重程度相关性分析

发布时间：2018-09-10 12:14

【摘要】：目的:探讨急性胰腺炎局部并发症的发生率及严重程度与病因相关性。方法:采用回顾性分析方法,收集我市部分三甲医院2010-2015年2227例急性胰腺炎(Acute pancreatitis AP)患者一般资料,分析其病因与局部并发症发生率以及严重程度的相关性。结果:研究中2227例急性胰腺炎患者病因分布为胆源性1137例(51.0%),代谢性741例(33.3%),酒精性349例(15.7%);局部并发症的总发生率为39%,其中胆源性489例(43.0%),代谢性269例(36.3%),酒精性111例(31.6%),胆源性AP局部并发症的发生率高于其他两组,酒精性与代谢性AP局部并发症发生率无统计学差异,按照胰周渗液累及的部位、数量将局部并发症分为轻中重三级,性别、年龄对于局部并发症的严重程度均无统计学差异(P0.05),胆源性AP局部并发症比代谢性AP(P=0.000)和酒精性AP严重(P=0.015),代谢性AP和酒精性AP在局部并发症的严重程度上无明显差异(P0.05)。结论:胆源性AP局部并发症发生率高于代谢性组和酒精性组,胆源性组的局部并发症也较其他两组严重,可见保守治疗对于胆源性AP的疗效不及其他病因类型的AP,因此在临床上处理胆源性AP时应及时解除胆道梗阻,而不能仅仅对炎症渗出情况进行干预。
[Abstract]:Objective: to investigate the incidence and severity of local complications in acute pancreatitis. Methods: the general data of 2227 patients with acute pancreatitis (Acute pancreatitis AP) from 2010 to 2015 in some third Class A Hospitals of our city were collected by retrospective analysis, and the correlation between the etiology and the incidence of local complications as well as the severity of acute pancreatitis was analyzed. Results: the etiology of 2227 patients with acute pancreatitis were choledochogenic 1137 (51.0%), metabolic 741 (33.3%), alcoholic 349 (15.7%), and the total incidence of local complications was 390.The total incidence of local complications was 398cases (43.0%), including 489 cases (43.0%), 269cases (36.3%), 111cases (31.6%). The incidence of local complications of biliary AP was higher than that of the other two groups. There was no significant difference in the incidence of local complications between alcoholic and metabolic AP. According to the location of peripancreatic effusion, the number of local complications was divided into light, medium and heavy levels, sex, Age had no significant difference in the severity of local complications (P0.05). Local complications of biliary AP were more serious than those of metabolic AP (P0. 000) and alcoholic AP (P0. 015). There was no significant difference in the severity of local complications between metabolic AP and alcoholic AP (P0.05). Conclusion: the incidence of local complications of biliary AP is higher than that of metabolic and alcoholic groups, and the local complications of biliary AP are more serious than those of the other two groups. It can be seen that the curative effect of conservative treatment on biliary AP is not as good as that of other etiological types of AP,. Therefore, the biliary obstruction should be relieved in clinical treatment of biliary AP, and the inflammatory exudation should not be interfered with.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R576

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