内镜下金属钛夹联合注射肾上腺素治疗消化性溃疡出血的疗效分析

发布时间：2018-11-08 08:39

【摘要】：目的探讨内镜下金属钛夹联合注射肾上腺素治疗消化性溃疡出血的临床疗效,评价治疗的有效性及安全性。方法将2012年3月-2014年3月该院经急诊胃镜检查确诊为消化性溃疡出血(内镜下Forrest分级为Ia、Ib、IIa和IIb)的158例患者,随机分为实验组和对照组,每组各79例,实验组采用金属钛夹联合注射肾上腺素治疗,对照组采用单纯注射肾上腺素治疗,比较两组治疗效果及并发症。结果两组即时止血率均为100.00%,实验组再出血率为1.27%(1/79),对照组为6.33%(5/79),两组比较差异有统计学意义(P0.05),外科手术率实验组为0.00%,对照组为2.54%(2/79),两组比较差异有统计学意义(P0.05)。全部病例均未出现穿孔及其他术后并发症。结论内镜下金属钛夹联合注射肾上腺素治疗消化性溃疡出血是一种疗效高、创伤低、并发症少的治疗方法,具有一定的临床价值。
[Abstract]:Objective to evaluate the efficacy and safety of endoscopic titanium clip combined with epinephrine injection in the treatment of peptic ulcer bleeding. Methods from March 2012 to March 2014, 158 patients with peptic ulcer bleeding (Forrest classified as Ia,Ib,IIa and IIb under endoscope) were randomly divided into experimental group and control group with 79 cases in each group. The experimental group was treated with titanium clip combined with epinephrine injection, while the control group was treated with epinephrine alone. The therapeutic effects and complications of the two groups were compared. Results the hemostasis rate of the two groups was 100.00g. The rebleeding rate was 1.27% (1 / 79) in the experimental group and 6.33% (5 / 79) in the control group. The difference between the two groups was statistically significant (P0.05). The surgical rate was 0.004% in the experimental group and 2.54% (2 / 79) in the control group. The difference between the two groups was statistically significant (P0.05). No perforation or other postoperative complications were found in all cases. Conclusion Endoscopic titanium clip combined with epinephrine injection for peptic ulcer haemorrhage is a method with high curative effect, low trauma and less complications, and has certain clinical value.
【作者单位】：北京大学首钢医院消化科;
【分类号】：R573.1

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