腹水浓缩回输联合腹腔内注药治疗肝硬化难治性腹水效果观察
发布时间：2018-11-18 17:42
【摘要】：目的观察腹水浓缩回输联合腹腔内注药治疗肝硬化难治性腹水的效果,并探讨其机制。方法 60例肝硬化难治性腹水患者随机分为观察组和对照组各30例,分别予腹水浓缩回输联合腹腔内注药和单纯腹水浓缩回输治疗,比较两组疗效及24 h尿量,检测两组治疗前后血清胆红素(TBil)、ALT、AST、血氨(NH3)、白蛋白(ALB),采用ELISA法检测两组血清肾素、醛固酮及血管紧张素Ⅱ。结果观察组总有效率高于对照组(P0.05);治疗后观察组血清TBi L低于对照组,ALB和24 h尿量均高于对照组(P均0.05);观察组肾素、醛固酮和血管紧张素Ⅱ明显低于对照组(P均0.05)。其余指示差异无统计学意义。结论腹水浓缩回输联合腹腔内注药治疗肝硬化难治性腹水疗效较好,其作用机制可能与抑制肾素-血管紧张素-醛固酮系统有关。
[Abstract]:Objective to observe the effect of concentrated ascites infusion combined with intraperitoneal injection in the treatment of refractory ascites of liver cirrhosis and its mechanism. Methods 60 patients with refractory ascites of liver cirrhosis were randomly divided into observation group (n = 30) and control group (n = 30). Serum bilirubin (TBil), ALT,AST, serum ammonia (NH3) was detected before and after treatment, albumin (ALB), was used to detect serum renin, aldosterone and angiotensin 鈪，
本文编号：2340693
[Abstract]:Objective to observe the effect of concentrated ascites infusion combined with intraperitoneal injection in the treatment of refractory ascites of liver cirrhosis and its mechanism. Methods 60 patients with refractory ascites of liver cirrhosis were randomly divided into observation group (n = 30) and control group (n = 30). Serum bilirubin (TBil), ALT,AST, serum ammonia (NH3) was detected before and after treatment, albumin (ALB), was used to detect serum renin, aldosterone and angiotensin 鈪，
本文编号：2340693
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