不同发病时间急性胆囊炎患者胆汁细菌培养结果分析

发布时间：2018-11-26 17:14

【摘要】：目的分析不同发病时间急性胆囊炎患者胆汁细菌培养结果。方法急性胆囊炎患者332例,均接受胆囊切除术治疗,根据发病时间分为24 h(121例)、24~72 h(113例)、72 h(98例)三组,术中常规抽取胆汁行细菌培养及鉴定。结果 332例急性胆囊炎患者胆汁细菌培养阳性260例,阳性率为78.3%。发病时间24 h、24~72 h、72 h患者胆汁培养阳性分别为82、86、92例,单一细菌生长分别为77、74、65例,多重细菌生长分别为5、12、27例,72 h者与前两者比较P均0.01。260例共培养出细菌309株,前五位的细菌分别为大肠埃希菌、粪肠球菌、屎肠球菌、铜绿假单胞菌、肺炎克雷伯杆菌,发病时间24 h、24~72 h、72 h患者培养出革兰阴性菌分别为49、52、73株,革兰阳性菌分别为43、38、44株,真菌分别为1、4、5株,72 h者与前两者比较P均0.01。结论发病时间72 h较24 h、24~72 h急性胆囊炎患者胆汁细菌培养阳性率高、多重细菌感染多、革兰阴性菌感染率高。
[Abstract]:Objective to analyze the results of bacterial culture in bile of patients with acute cholecystitis. Methods 332 patients with acute cholecystitis were treated with cholecystectomy. According to the time of cholecystectomy, they were divided into three groups: 24 h (121 cases), 24 h (113 cases), 72 h (98 cases). Results among 332 patients with acute cholecystitis, 260 cases were positive in bile culture, the positive rate was 78.3%. The positive rates of bile culture, single bacterial growth and multiple bacteria growth were 82 / 866 / 92, 77 / 744 / 65 and 5 / 121227 respectively in the patients with 24 h / 24 / 72 / 72 h, respectively. Compared with the former two groups, 309 strains of bacteria were cultured in 72 h patients (P 0.01.260). The first five bacteria were Escherichia coli, Enterococcus faecalis, Enterococcus faecium, Pseudomonas aeruginosa and Klebsiella pneumoniae. The number of Gram-positive bacteria and fungi were 43, 3884 and 5, respectively (P < 0. 01) for 72 h compared with the former (P < 0. 01). Conclusion the positive rate of bile bacteria culture was higher in patients with acute cholecystitis at 72 hours after onset than in patients with acute cholecystitis at 24 hours or 24 hours, and the infection rate of Gram-negative bacteria was higher than that of multiple bacterial infections.
【作者单位】：上海市徐汇区大华医院;同济大学附属同济医院;
【分类号】：R575.61

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