幽门螺杆菌感染对肠易激综合征及分型的影响

发布时间：2018-12-06 19:02

【摘要】：目的探讨幽门螺杆菌感染对肠易激综合征及其分型的影响作用,为临床治疗提供参考依据。方法选择2013年1月-2015年12月浙江省荣军医院消化内科胃十二指肠疾病患者189例,将其分为观察组(幽门螺杆菌阳性组)135例和对照组(幽门螺杆菌阴性组)54例;比较观察组和对照组患者肠易激综合征的发病率及不同分型肠易激综合征的发病率,观察幽门螺杆菌根除对肠易激综合征症状的影响。结果观察组肠易激综合征的发病率为40.7%,显著高于对照组24.1%(P0.05);观察组腹泻型、便秘型、混合型、不定型肠易激综合征的发病率与对照组比较,差异均无统计学意义;幽门螺杆菌根除成功组肠易激综合征的症状缓解率为76.9%,高于失败组43.8%(P0.05)。结论幽门螺杆菌感染增加肠易激综合征的发病率,对肠易激综合征的分型无影响,幽门螺杆菌根除治疗可以提高肠易激综合征的症状缓解率。
[Abstract]:Objective to investigate the effect of Helicobacter pylori infection on irritable bowel syndrome and its classification. Methods 189 patients with gastroduodenal diseases in Department of Digestive Medicine, Rongjun Hospital, Zhejiang Province, from January 2013 to December 2015, were divided into observation group (HP positive group) and control group (HP negative group, n = 135) and control group (Helicobacter pylori negative group, n = 54). The incidence of irritable bowel syndrome and the incidence of different types of irritable bowel syndrome were compared between the observation group and the control group, and the effects of Helicobacter pylori eradication on the symptoms of the irritable bowel syndrome were observed. Results the incidence of irritable bowel syndrome in the observation group was 40.7, which was significantly higher than that in the control group (24.1%) (P0.05). The incidence of diarrhea, constipation, mixed, and irritable bowel syndrome in the observation group was not significantly different from that in the control group. The remission rate of irritable bowel syndrome in the successful eradication group was 76.9%, which was higher than that in the failed group (43.8%) (P0.05). Conclusion Helicobacter pylori infection increases the incidence of irritable bowel syndrome and has no effect on the classification of irritable bowel syndrome. Helicobacter pylori eradication therapy can improve the remission rate of irritable bowel syndrome.
【作者单位】：浙江荣军医院消化内科;嘉兴市第二医院检验科;
【基金】：浙江省医药卫生研究计划基金资助项目(2014KYA211)
【分类号】：R574.4

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