经门静脉左、右支TIPS治疗门静脉高压疗效比较

发布时间：2018-12-20 16:33

【摘要】：目的：探讨经门静脉左支与右支的TIPS术治疗肝硬化合并门静脉高压患者的疗效。方法：64例患者按入院先后顺序进行编号后，单号分配到TIPS-LBPV组（共32例,其中2名患者操作失败）、双号分配到TIPS-RBPV组（共32例）。62例患者术后随访1年。实验中34例患者分别抽取门静脉左、右支的血，检测血氨浓度，，并进行统计学比较。结果：门静脉左支血氨浓度低于门静脉右支（p=0.01）。两种术式在降低门静脉压力方面的效果类似（p㧐0.05）。TIPS-LBPV组术后肝性脑病的发生率低于TIPS-RBPV组（p=0.036）。TIPS-LBPV组术后支架功能异常的发生率也低于TIPS-RBPV组（p=0.042）。结论：门静脉左支的血氨浓度低于门静脉右支，行TIPS-LBPV术的患者术后肝性脑病及支架功能异常的发生率低于接受TIPS-RBPV术的患者。
[Abstract]:Objective: to evaluate the efficacy of TIPS in the treatment of cirrhotic patients with portal hypertension. Methods: 64 patients were assigned to TIPS-LBPV group (32 cases) and even number group (32 cases) to TIPS-RBPV group. 62 patients were followed up for 1 year. Blood samples from left and right branches of portal vein were collected from 34 patients, and blood ammonia concentrations were measured and compared statistically. Results: the concentration of ammonia in the left branch of portal vein was lower than that in the right branch of portal vein (p0. 01). The incidence of hepatic encephalopathy in TIPS-LBPV group was lower than that in TIPS-RBPV group (p0. 036). The incidence of abnormal stent function in TIPS-LBPV group was also lower than that in TIPS-LBPV group. It was lower than that in TIPS-RBPV group (p0. 042). Conclusion: the concentration of ammonia in the left branch of portal vein is lower than that in the right branch of portal vein. The incidence of hepatic encephalopathy and abnormal stenting in TIPS-LBPV patients is lower than that in TIPS-RBPV patients.
【学位授予单位】：青海大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R575.2

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