四磨汤联合甘露醇对磁控胶囊内镜肠道准备效果的作用

发布时间：2019-02-14 20:19

【摘要】：目的·观察四磨汤联合甘露醇对磁控胶囊内镜检查前的肠道准备效果。方法·采用随机对照试验,选择拟行磁控胶囊内镜检查的患者120例,按照随机数字表法将患者随机分为2组,每组60例。观察组在磁控胶囊内镜检查前1日口服四磨汤20 mL,每日3次,再分次口服甘露醇500 mL;对照组直接分次口服甘露醇500 mL。观察患者服药后肠道清洁度以及不良反应发生情况。结果·观察组肠道气泡量少于对照组(Z=-1.976,P=0.048),肠液量也少于对照组(Z=-2.489,P=0.013)。观察组出现恶心、呕吐症状的评分低于对照组(Z=-2.215,P=0.027),发生腹胀、腹痛、肛门不适症状的评分同样低于对照组(Z=-2.158,P=0.031);2组总体不良反应发生率分别为8.33%、36.67%(χ~2=13.811,P=0.000)。结论·四磨汤联合甘露醇能提高肠道清洁度,减轻患者不良反应,改善肠道准备效果。
[Abstract]:Objective to observe the effect of Simo decoction combined with mannitol on intestinal preparation before endoscopy of magnetron capsule. Methods A randomized controlled trial was conducted in 120 patients with magnetic control capsule endoscopy. The patients were randomly divided into 2 groups (60 cases in each group) according to the method of random digital table. The observation group took Simo decoction 3 times a day 3 times a day one day before endoscopy of magnetron capsule and mannitol 500 mL; once a day. The control group took mannitol 500 mL. directly. To observe the degree of intestinal cleanliness and the occurrence of adverse reactions after taking medicine. Results the number of intestinal air bubbles in the observation group was less than that in the control group (Z _ (-1.976) P _ (0.048) and the intestinal fluid volume was also lower than that in the control group (Z _ (-2.489) P _ (0.013). The scores of nausea and vomiting in the observation group were lower than those in the control group (ZP0. 027), abdominal distension, abdominal pain and anal discomfort were also lower than those in the control group (ZC- 2. 158, P0. 031). The overall incidence of adverse reactions in the two groups was 8.33 and 36.67% respectively (蠂 ~ 2 ~ (13.811) P ~ (0.000). Conclusion Simo decoction combined with mannitol can improve intestinal cleanliness, alleviate adverse reactions and improve intestinal preparation.
【作者单位】：上海交通大学附属第六人民医院消化内科;
【基金】：上海交通大学附属第六人民医院科研基金(1776) 上海市科学技术委员会西医引导项目(17411966500)~~
【分类号】：R57

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