64排螺旋CT对原发性胆汁性肝硬化患者肝脏体积变化的研究——与乙肝肝硬化和正常人对比研究

发布时间：2019-03-16 10:25

【摘要】：目的应用64排螺旋CT测量肝脏体积,探讨原发性胆汁性肝硬化(PBC)失代偿期患者肝脏体积变化的特点。方法搜集PBC住院患者48例作为PBC组,同期搜集乙型肝炎病毒相关肝硬化患者64例作为HBC组,并随机选取同期52例正常人作为对照组,所有病例均行腹部CT增强扫描,将门静脉期图像分解后所获得的轴面图像数据传输至GE Advantage Workstation 4.4,重建并计算出肝脏体积,计算出标准化的肝脏体积后,应用SPSS15.0统计软件,对三组肝体积均数的总体差异和两两组间差异进行比较。结果 (1)比较PBC组、HBC组、对照组的CT测量肝脏体积和标准化肝体积的差异均有统计学意义(F=7.435,P=0.024;F=4.862,P=0.012);(2)分别比较两两组间CT测量肝脏体积和标准化肝体积的差异,其中PBC组与HBC组之间、HBC组与对照组之间的差异均有统计学意义(P0.05),PBC组与对照组的差异均无统计学意义(P0.050)。结论 PBC倾向好发于女性,失代偿期肝脏体积缩小不显著,部分仍呈弥漫性增大。
[Abstract]:Aim to investigate the characteristics of liver volume changes in patients with primary biliary cirrhosis during decompensation of (PBC) by 64-slice spiral CT. Methods 48 patients with PBC were collected as PBC group, 64 patients with hepatitis B virus-associated cirrhosis were collected as HBC group at the same time, and 52 normal subjects were randomly selected as control group. All patients were performed abdominal CT enhanced scan. After decomposing the portal phase images, the axial image data were transmitted to GE Advantage Workstation 4.4, the liver volume was reconstructed and calculated, and the standardized liver volume was calculated. Then the SPSS15.0 statistical software was used. The total difference of liver volume between the three groups and the difference between the two groups were compared. Results (1) there was significant difference between PBC group, HBC group and control group in the measurement of liver volume and standardized liver volume (F = 7.435, P = 0.024 / F = 4.862, P = 0.012). (2) the differences of liver volume and standardized liver volume measured by CT between the two groups were compared. There was significant difference between PBC group and HBC group, and between HBC group and control group (P0.05). There was no significant difference between PBC group and control group (P 0.050). Conclusion PBC tends to occur in women, liver volume is not significantly reduced during decompensation, and some of them are still diffusely enlarged.
【作者单位】：首都医科大学附属北京友谊医院放射科;
【分类号】：R575.2;R816.5

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