血清ALT水平升高非酒精性脂肪性肝病患者代谢相关指标水平变化
发布时间:2019-06-06 07:22
【摘要】:目的观察血清丙氨酸氨基转移酶(ALT)水平升高非酒精性脂肪性肝病(NAFLD)患者代谢相关指标变化。方法 NAFLD患者1 273例,将其中256例血清ALT水平40 U/L者作为ALT升高组,256例血清ALT水平≤40 U/L者作为ALT正常组,同时选取256例非NAFLD者作为对照组。比较三组BMI、收缩压(SBP)、舒张压(DBP)、血清尿酸(UA)、TG、TC、LDL-C、HDL-C、空腹血糖(FPG),比较ALT升高组与ALT正常组超重及肥胖、高血压、高尿酸血症、高脂血症、高血糖患病率,分析NAFLD患者血清ALT水平升高的危险因素。结果 NAFLD患者ALT升高组TC、LDL-C、FPG水平及高脂血症、高血糖患病率均高于ALT正常组(P均0.05)。多因素Logistic回归分析结果显示,高LDL-C(P=0.000,95%CI:1.358~2.807)和高血糖(P=0.001,95%CI:1.366~3.386)均为NAFLD患者血清ALT水平升高的独立危险因素。结论血清ALT水平升高NAFLD患者TC、LDL-C、FPG水平高,高脂血症、高血糖患病率高,危险因素为高LDL-C和高血糖。
[Abstract]:Objective to observe the changes of metabolism related indexes in patients with non-alcoholic fatty liver disease (NAFLD) with elevated serum alanine aminotransferase (ALT) level. Methods 1273 patients with NAFLD were enrolled in this study. 256 patients with serum ALT level 40 U 鈮,
本文编号:2494166
[Abstract]:Objective to observe the changes of metabolism related indexes in patients with non-alcoholic fatty liver disease (NAFLD) with elevated serum alanine aminotransferase (ALT) level. Methods 1273 patients with NAFLD were enrolled in this study. 256 patients with serum ALT level 40 U 鈮,
本文编号:2494166
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