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Recql5 protects against lipopolysaccharide/D-galactosamine-i

发布时间:2021-04-16 04:20
  AIM: To investigate the effects of Recql5 deficiency on liver injury induced by lipopolysaccharide/D-galactosamine(LPS/D-Gal).METHODS: Liver injury was induced in wild type(WT) or Recql5-deficient mice using LPS/D-Gal,and assessed by histological,serum transaminases,and mortality analyses. Hepatocellular apoptosis was quantified by transferase d UTP nick end labeling assay and Westernblot analysis of cleaved caspase-3. Liver inflammatory chemokine and cytochrome P450 expression was analyzed by q... 

【文章来源】:World Journal of Gastroenterology. 2015,21(36)SCI

【文章页数】:10 页

【参考文献】:
期刊论文
[1]Effect of Recql5 deficiency on the intestinal tumor susceptibility of Apcmin mice[J]. Yiduo Hu,Xincheng Lu,Guangbin Luo,Department of Genetics,Case Comprehensive Cancer Center and University Hospitals of Cleveland,Case Western Reserve University,Cleveland,OH 44106,United States Yiduo Hu,Department of Cancer Biology,Dana-Farber Cancer Institute,Boston,MA 02115,United States.  World Journal of Gastroenterology. 2010(12)



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