幽门螺杆菌感染与非酒精性脂肪肝的相关性分析

发布时间：2021-07-27 12:59

　　目的探讨幽门螺杆菌（H.pylori）感染与非酒精性脂肪肝（NAFLD）之间的关系,分析H.pylori感染可能介导NAFLD发病的潜在介质,为预防及治疗NAFLD提供新策略。方法采用横断面调查研究方法,收集位于宁夏银川市的美年大健康大型体检机构在2018年1月-2018年12月期间同时行碳14尿素呼气试验和腹部彩超的体检人群为研究对象。根据纳入和排除标准,按照随机抽样的方法,最终将3947例符合标准的研究对象纳入研究。根据是否患有NAFLD,将其分为NAFLD（-）组（2987人）和NAFLD（+）组（960人）,对两组资料的一般信息（性别、年龄）、BMI、SBP、DBP、FPG、TC、TG、HDL-C、LDL-C、AST、ALT、UA、白细胞计数和H.pylori感染情况进行统计分析,然后将上述因素中有统计学意义的指标纳入二元Logistic回归分析影响NAFLD的危险因素。同时在不同性别、年龄、BMI分层中,分析H.pylori感染情况对NAFLD影响。另外将所有体检人群根据H.pylori感染情况为H.pylori阳性组（n=2081人）与H.pylori阴性组（n=1866人... 

【文章来源】：西北民族大学甘肃省

【文章页数】：39 页

【学位级别】：硕士

【部分图文】：

血脂异常人群中H.pylori感染情况与NAFLD患病率

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