ERCP术后胰腺炎及高淀粉酶血症危险因素分析及预防性应用肾上腺素的效果研究
发布时间:2021-09-04 21:02
目的:分析经内镜逆行胰胆管造影术(Endoscopic Retrograde Cholangiopancreatography,ERCP)术后胰腺炎(post-ERCP pancreatitis,PEP)及高淀粉酶血症(Hyperamylasemia)的危险因素及研究预防性应用肾上腺素的效果。方法:本研究选取于河北医科大学第二医院在胆道微创外科2017年01月至2018年01月,术前诊断为胆总管结石行ERCP的患者,共239例符合纳入标准。设计表格,收集相关资料。最终确定ERCP术后胰腺炎及高淀粉酶发生率的相关危险因素、独立危险因素及预防性应用肾上腺素的效果。将相关危险因素进行单因素分析,对有统计学意义(P<0.05)的因素进行多因素logistic回归性分析。结果:纳入239例患者中,9例患者出现ERCP术后胰腺炎,发生率为3.76%(9例/239例),76例患者被临床诊断为ERCP术后高淀粉酶血症,发生率为31.79%(76例/239例)。PEP单因素分析取石网篮进入胰管、胆总管结石直径(≤0.6cm)、困难插管(≥10分钟)为危险因素,肾上腺素为保护性因素。PEP多因素分析...
【文章来源】:河北医科大学河北省
【文章页数】:47 页
【学位级别】:硕士
【文章目录】:
中文摘要
英文摘要
英文缩写
前言
材料与方法
结果
附表
讨论
结论
参考文献
综述 ERCP术后相关并发症的防治进展
参考文献
致谢
个人简历
【参考文献】:
期刊论文
[1]Post-endoscopic retrograde cholangiopancreatography pancreatitis: Risk factors and predictors of severity[J]. Ayman El Nakeeb,Ehab El Hanafy,Tarek Salah,Ehab Atef,Hosam Hamed,Ahmad M Sultan,Emad Hamdy,Mohamed Said,Ahmed A El Geidie,Tharwat Kandil,Mohamed El Shobari,Gamal El Ebidy. World Journal of Gastrointestinal Endoscopy. 2016(19)
[2]十二指肠乳头局部喷洒肾上腺素对胆总管结石ERCP术后胰腺炎的预防作用[J]. 王广勇,施云星,吕礁,曾晓虹,周国中,刘长云,钱慧. 中华胰腺病杂志. 2015 (06)
[3]Preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: What can be done?[J]. Goran Hauser,Marko Milosevic,Davor Stimac,Enver Zerem,Predrag Jovanovi?,Ivana Blazevic. World Journal of Gastroenterology. 2015(04)
[4]Endoscopic treatment of duodenal fistula after incomplete closure of ERCP-related duodenal perforation[J]. Dong Wook Yu,Man Yong Hong,Seung Goun Hong. World Journal of Gastrointestinal Endoscopy. 2014(06)
[5]Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: A meta-analysis[J]. Qing-Qing Shi,Xiao-Yi Ning,Ling-Ling Zhan,Guo-Du Tang,Xiao-Ping Lv. World Journal of Gastroenterology. 2014(22)
[6]Effect of precut sphincterotomy on post-endoscopic retrograde cholangiopancreatography pancreatitis:A systematic review and meta-analysis[J]. Abhishek Choudhary,Jessica Winn,Sameer Siddique,Murtaza Arif,Zainab Arif,Ghassan M Hammoud,Srinivas R Puli,Jamal A Ibdah,Matthew L Bechtold. World Journal of Gastroenterology. 2014(14)
[7]治疗性ERCP术后胰腺炎危险因素的Logistic回归分析[J]. 陈小微,洪万东,吴小丽,黄庆科,朱启槐. 实用医学杂志. 2012(04)
[8]内镜下逆行胆胰管造影术(ERCP)诊治指南(2010版)[J]. 中华医学会消化内镜分会ERCP学组,胡冰,麻树人,李兆申. 中国继续医学教育. 2010(06)
[9]Treating delayed endoscopic sphincterotomy-induced bleeding:Epinephrine injection with or without thermotherapy[J]. Yung-Kuan Tsou,Nai-Jen Liu,Jui-Hsiang Tang,Kai-Feng Sung,Chi-Liang Cheng,Ching-Song Lee. World Journal of Gastroenterology. 2009(38)
[10]N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis[J]. Janusz Milewski,Grazyna Rydzewska,Malgorzata Degowska,Maciej Kierzkiewicz,Andrzej Rydzewski. World Journal of Gastroenterology. 2006(23)
本文编号:3384002
【文章来源】:河北医科大学河北省
【文章页数】:47 页
【学位级别】:硕士
【文章目录】:
中文摘要
英文摘要
英文缩写
前言
材料与方法
结果
附表
讨论
结论
参考文献
综述 ERCP术后相关并发症的防治进展
参考文献
致谢
个人简历
【参考文献】:
期刊论文
[1]Post-endoscopic retrograde cholangiopancreatography pancreatitis: Risk factors and predictors of severity[J]. Ayman El Nakeeb,Ehab El Hanafy,Tarek Salah,Ehab Atef,Hosam Hamed,Ahmad M Sultan,Emad Hamdy,Mohamed Said,Ahmed A El Geidie,Tharwat Kandil,Mohamed El Shobari,Gamal El Ebidy. World Journal of Gastrointestinal Endoscopy. 2016(19)
[2]十二指肠乳头局部喷洒肾上腺素对胆总管结石ERCP术后胰腺炎的预防作用[J]. 王广勇,施云星,吕礁,曾晓虹,周国中,刘长云,钱慧. 中华胰腺病杂志. 2015 (06)
[3]Preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: What can be done?[J]. Goran Hauser,Marko Milosevic,Davor Stimac,Enver Zerem,Predrag Jovanovi?,Ivana Blazevic. World Journal of Gastroenterology. 2015(04)
[4]Endoscopic treatment of duodenal fistula after incomplete closure of ERCP-related duodenal perforation[J]. Dong Wook Yu,Man Yong Hong,Seung Goun Hong. World Journal of Gastrointestinal Endoscopy. 2014(06)
[5]Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: A meta-analysis[J]. Qing-Qing Shi,Xiao-Yi Ning,Ling-Ling Zhan,Guo-Du Tang,Xiao-Ping Lv. World Journal of Gastroenterology. 2014(22)
[6]Effect of precut sphincterotomy on post-endoscopic retrograde cholangiopancreatography pancreatitis:A systematic review and meta-analysis[J]. Abhishek Choudhary,Jessica Winn,Sameer Siddique,Murtaza Arif,Zainab Arif,Ghassan M Hammoud,Srinivas R Puli,Jamal A Ibdah,Matthew L Bechtold. World Journal of Gastroenterology. 2014(14)
[7]治疗性ERCP术后胰腺炎危险因素的Logistic回归分析[J]. 陈小微,洪万东,吴小丽,黄庆科,朱启槐. 实用医学杂志. 2012(04)
[8]内镜下逆行胆胰管造影术(ERCP)诊治指南(2010版)[J]. 中华医学会消化内镜分会ERCP学组,胡冰,麻树人,李兆申. 中国继续医学教育. 2010(06)
[9]Treating delayed endoscopic sphincterotomy-induced bleeding:Epinephrine injection with or without thermotherapy[J]. Yung-Kuan Tsou,Nai-Jen Liu,Jui-Hsiang Tang,Kai-Feng Sung,Chi-Liang Cheng,Ching-Song Lee. World Journal of Gastroenterology. 2009(38)
[10]N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis[J]. Janusz Milewski,Grazyna Rydzewska,Malgorzata Degowska,Maciej Kierzkiewicz,Andrzej Rydzewski. World Journal of Gastroenterology. 2006(23)
本文编号:3384002
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