双气囊小肠镜（DBE）和胶囊内镜（CE）对可疑小肠疾病诊断价值研究

发布时间：2021-09-05 05:55

　　研究背景小肠是人体消化道最长的器官,由于传统侵袭性检查手段的限制,如推进式内镜（push enteroscopy,PE）只能进入近端小肠对小肠病变进行诊治,结肠镜也只能进入回肠末端进行观察,因此,既往小肠被认为是消化道检查的盲区。既往认为小肠疾病（small bowel diseases, SBDs）发病率较低,临床表现非特异,小肠又位于消化道较深的位置,SBDs的诊断和后续治疗常常被延迟,给SBDs患者造成严重的经济负担和不良的预后,这就使得SBDs的早期识别、诊断和干预在临床实践中显得极为重要。随着胶囊内镜（capsule endoscopy, CE）和气囊辅助内镜（balloon-assisted enteroscopy, BAE）的临床应用,使得SBDs得以及时的诊断,同时又可以获得小肠粘膜的病理学诊断,从而使SBDs诊治进入了一个新时代。CE,又称无线胶囊内镜（wireless CE）,是本世纪初消化内镜领域一项重大发明,最初由以色列Given公司研发和生产。相对于传统的非侵袭性小肠检查如利用放射学检查的消化道钡餐、CT, CE能随自身肠蠕动对肠道粘膜进行观察,具有非侵袭性、... 

【文章来源】：南方医科大学广东省

【文章页数】：129 页

【学位级别】：博士

【文章目录】：
摘要
ABSTRACT
第一部分 双气囊小肠镜对可疑小肠疾病诊断价值研究
    引言
    资料与方法
    统计方法
    结果
    结论
    讨论
    参考文献
第二部分 双气囊小肠镜和胶囊内镜对Meckel憩室诊断价值研究
    引言
    资料和方法
    统计方法
    结果
    结论
    讨论
    参考文献
第三部分 双气囊小肠镜和胶囊内镜对小肠间叶组织肿瘤诊断价值研究
    引言
    资料与方法
    统计方法
    结果
    讨论
    参考文献
第四部分 胶囊内镜与CTE/MRI对可疑小肠疾病诊断价值研究：系统回顾与Meta分析
    引言
    资料与方法
    统计方法
    结果
    讨论
    参考文献
全文小结
缩略语英文对照
攻读博士期间发表与待发表研究
致谢
统计学证明


【参考文献】：
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