Association of mRNA Expression Level of IP-10 in Peripheral

发布时间：2023-05-07 14:12

　　HBV-associated acute-on-chronic liver failure is prevalent in China’s mainland. The prognosis of HBV-ACLF is poor. The mortality of HBV-ACLF is approximately 80%. Therefore, a prognostic indicator was needed in order to allow us to intervene as soon as possible. The model for end-stage liver disease(MELD) scoring system is widely used to predict the prognosis of liver failure. However, the assessment is too complex to restrict its application. This study aimed to investigate the expression of IP...

【文章页数】：6 页

【文章目录】：
1
    MATERIALS
    AND
    METHODS 1.1
    Subjects 1.2
    Reagents
    and
    Instruments 1.3
    Sample
    Collection 1.4
    Total
    RNA
    Extraction 1.5
    PCR
    Primer
    Design 1.6
    c
    DNA
    Synthesis 1.7
    Fluorescent
    Quantitative
    PCR 1.8
    Calculation 1.9
    Statistical
    Analysis 2
    RESULTS 2.1
    IP-10
    Expression
    in
    PBMCs
    of
    Patients
    with
    HBV-ACLF 2.2
    Positive
    Correlation
    between
    IP-10
    m
    RNA
    Level
    in
    PBMCs
    and
    Severity
    of
    Liver
    Failure
    in
    HBV-ACLF
    Patients 2.3
    Positive
    Correlation
    between
    IP-10
    m
    RNA
    Level
    in
    PBMCs
    and
    Serum
    ALT
    in
    HBV-ACLF 2.4
    The
    IP-10
    m
    RNA
    Level
    in
    PBMCs
    Positively
    Correlated
    with
    Serum
    Total
    Bilirubin
    inHBV-ACLF 2.5
    Correlation
    Analysis
    of
    IP-10
    m
    RNA
    Level
    in
    PBMCs
    and
    Serum
    INR
    in
    HBV-ACLF
    Patients 2.6
    Negative
    Correlation
    between
    IP-10
    m
    RNA
    Level
    and
    Serum
    HBs
    Ag
    in
    HBV-ACLF 2.7
    Relationship
    of
    IP-l0
    m
    RNA
    Level,
    Serum
    HBs
    Ag
    and
    Other
    Clinical
    Indexes
    with
    Prognosis
    of
    Patients
    with
    HBV-ACLF 2.8
    Analysis
    of
    Area
    under
    Receiver
    Operating
    Characteristic
    (ROC)
    Curves 3
    DISCUSSION Conflict
    of
    Interest
    Statement



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