渗出性年龄相关性黄斑变性在眼底自发荧光及红外光中的影像特征
发布时间：2018-11-27 07:38
【摘要】：目的：观察和比较渗出性年龄相关性黄斑变性(age-related maculardegeneration，AMD)不同类型的眼底自发荧光(autofluorescence，AF)和红外光(infrared ray，IR)的影像特征。 方法：对23眼渗出性AMD患者进行自发荧光(AF)、红外光(IR)、荧光素眼底血管造影(FFA)、吲哚菁绿脉络膜血管造影(ICGA)、光学相干断层扫描(OCT)检查，观察、比较不同类型渗出性AMD患者眼底AF及IR特点。 结果：患者23眼中，有7眼为典型性CNV，9眼为隐匿性CNV，7眼为混合性CNV。在典型性CNV中，AF特征：7眼（100%）表现为病灶区明显低荧光，5眼（71.42%）见病灶外缘环绕相对增高的荧光环。IR特征：病灶区内主要为低荧光，在其外围围绕着环状或半环状高荧光。在隐匿型CNV中，，AF特征：隐匿性CNV有8例（88.89%）表现为斑驳样点状或片状低荧光，1例荧光无显著变化。IR特征：主要表现为散在的点状不均匀的高荧光灶，边界模糊不清。在混合型CNV中，AF特征：7例（100%）表现为片状低荧光区伴多发散在的斑驳样低荧光。IR特征：FFA渗漏区表现为低荧光，周围伴有散在高荧光。 结论：眼底自发荧光和红外光是目前集多种优点于一体的新型眼底成像技术。渗出性AMD患者眼底表现复杂多变，每种类型具有其不同的特征，因此AF及IR形态也多种多样。动态监测这些异常的AF及IR影像特点对评价不同类型渗出性年龄相关性黄斑变性的发病进展过程具有一定的临床意义。
[Abstract]:Aim: to observe and compare the imaging features of different types of fundus autofluorescence (autofluorescence,AF) and infrared light (infrared ray,IR) in exudative age related macular degeneration (age-related maculardegeneration,AMD). Methods: 23 eyes with exudative AMD were examined by (ICGA), optical coherence tomography (OCT) with (AF), infrared (IR), fluorescein angiography and (FFA), indocyanine green choroidal angiography. To compare the characteristics of fundus AF and IR in patients with different types of exudative AMD. Results: in 23 eyes, 7 eyes were typical CNV,9, occult CNV,7 eyes were mixed CNV.. In typical CNV, AF showed obvious hypofluorescence in 7 eyes (100%), low fluorescence in 5 eyes (71.42%) and low fluorescence in 5 eyes (71.42%). It is surrounded by annular or semi-annular high fluorescence. In occult CNV, AF features: 8 cases (88.89%) of occult CNV showed mottled dot or flake low fluorescence, while 1 case showed no significant change in fluorescence. The boundary is blurred. In mixed CNV, AF was found in 7 cases (100%) with flake low fluorescence region and multiple diffuse mottled low fluorescence, while IR showed low fluorescence in FFA leakage region and high fluorescence around it. Conclusion: fundus autofluorescence and infrared light are new fundus imaging techniques. The fundus manifestations of exudative AMD patients are complex and variable, and each type has its own characteristics. Therefore, the morphology of AF and IR is also varied. Dynamic monitoring of these abnormal AF and IR imaging features has certain clinical significance in evaluating the pathogenesis and progression of different types of exudative age-related macular degeneration.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R774.5
本文编号：2359895
[Abstract]:Aim: to observe and compare the imaging features of different types of fundus autofluorescence (autofluorescence,AF) and infrared light (infrared ray,IR) in exudative age related macular degeneration (age-related maculardegeneration,AMD). Methods: 23 eyes with exudative AMD were examined by (ICGA), optical coherence tomography (OCT) with (AF), infrared (IR), fluorescein angiography and (FFA), indocyanine green choroidal angiography. To compare the characteristics of fundus AF and IR in patients with different types of exudative AMD. Results: in 23 eyes, 7 eyes were typical CNV,9, occult CNV,7 eyes were mixed CNV.. In typical CNV, AF showed obvious hypofluorescence in 7 eyes (100%), low fluorescence in 5 eyes (71.42%) and low fluorescence in 5 eyes (71.42%). It is surrounded by annular or semi-annular high fluorescence. In occult CNV, AF features: 8 cases (88.89%) of occult CNV showed mottled dot or flake low fluorescence, while 1 case showed no significant change in fluorescence. The boundary is blurred. In mixed CNV, AF was found in 7 cases (100%) with flake low fluorescence region and multiple diffuse mottled low fluorescence, while IR showed low fluorescence in FFA leakage region and high fluorescence around it. Conclusion: fundus autofluorescence and infrared light are new fundus imaging techniques. The fundus manifestations of exudative AMD patients are complex and variable, and each type has its own characteristics. Therefore, the morphology of AF and IR is also varied. Dynamic monitoring of these abnormal AF and IR imaging features has certain clinical significance in evaluating the pathogenesis and progression of different types of exudative age-related macular degeneration.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R774.5
【共引文献】
相关期刊论文 前3条
1 胡迪;李寿玲;;眼底自发荧光影像及其临床应用进展[J];临床眼科杂志;2009年06期
2 ;Lipofuscin-and Melanin-related Fundus Autofluorescence in Patients with Submacular Idiopathic Choroidal Neovascularization[J];Eye Science;2012年03期
3 付校楠;彭惠;;眼底自发荧光技术在部分视网膜疾病中的应用进展[J];眼科新进展;2013年04期
本文编号：2359895
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