蓝莓花青素对小鼠抗疲劳及体内抗氧化作用

发布时间：2018-05-31 21:17

本文选题：蓝莓 + 花青素　；参考：《食品科学》2017年21期

【摘要】：目的:研究蓝莓花青素对小鼠抗疲劳和体内抗氧化的作用。方法:经灌胃给予小鼠低、中、高剂量蓝莓花青素30 d后,分别测定负重游泳时间、转棒时间,肝糖原(liver glycogen,LG)含量、肌糖原(muscle glycogen,MG)含量、血尿素氮(blood urea nitrogen,BUN)含量、血乳酸(blood lactic acid,BLA)含量、乳酸脱氢酶(lactic dehydrogenase,LDH)活力、肝脏总抗氧化能力(total antioxidant capacity,T-AOC)、总超氧化物歧化酶(total superoxide dismutase,T-SOD)活力、谷胱甘肽过氧化物歧化酶(glutathione peroxide dismutase,GSH-Px)活力及丙二醛(malondialdehyde,MDA)含量。结果:与空白对照组相比,蓝莓花青素低、中、高剂量组能显著延长小鼠负重游泳时间和转棒时间(P0.05,P0.01),蓝莓花青素低、中、高剂量组能使小鼠体内LG含量显著增加(P0.05),BLA、BUN和MDA含量明显降低(P0.05,P0.01),并能显著增加小鼠肝脏T-AOC和T-SOD、GSH-Px活力(P0.05)。蓝莓花青素中、高剂量组能使小鼠体内MG含量和LDH活力显著增加(P0.05,P0.01)。结论:结果表明蓝莓花青素具有较好的抗疲劳及体内抗氧化作用。
[Abstract]:Objective: to study the anti-fatigue and anti-oxidation effects of blueberry anthocyanins on mice. Methods: after 30 days of administration of low, middle and high doses of blueberry anthocyanins, the body weight swimming time, the turning time, the content of glycogen G, the content of muscle glycogen, the content of blood urea nitrogen urea nitrogenn and the content of blood lactate lactic were measured. The activity of lactate dehydrogenase (LDH), the total antioxidant capacity of liver total antioxidant capacity- T-AOC, total superoxide dismutase (T-SOD), glutathione peroxide dismutase (glutathione peroxide dismutase) activity and malondialdehyde (MDA) content were observed. Results: compared with the blank control group, the blueberry anthocyanins were lower, the middle and high dose groups could significantly prolong the weight bearing swimming time and the rotation time of the mice (P 0.05), and the blueberry anthocyanins were low, medium and low. In the high dose group, the contents of LG and MDA decreased significantly, and the activities of T-AOC and T-SOD GSH-Px in liver were significantly increased. In the blueberry anthocyanin group, the content of MG and the activity of LDH increased significantly in the high dose group. Conclusion: the results showed that blueberry anthocyanins had good anti-fatigue and anti-oxidation effects in vivo.
【作者单位】：北华大学林学院;吉林省长白山食品药品检测检验中心;
【基金】：吉林市科技计划项目(2015431015) 2016年国家级大学生创新项目(201610201013)
【分类号】：R151

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