中国三地区孕妇妊娠期间膳食与体内脂肪酸储备水平的关系

发布时间：2018-06-10 16:01

本文选题：血浆 + 磷脂酰胆碱　；参考：《卫生研究》2016年03期

【摘要】：目的调查中国三地区孕妇的膳食模式、血浆磷脂酰胆碱(PC)中多种脂肪酸的含量和它们之间的关系。方法选取淡水河湖(江苏句容)、沿海(山东日照)和内陆(河北徐水)地区各一处,与当地医院妇产科合作,每地区选取35位健康常住孕妇,通过问卷形式调查她们妊娠中期膳食情况,包括膳食频率与食用油消费量,并于妊娠晚期以气相色谱法检测其血浆PC中各种脂肪酸含量。结果日照孕妇海鱼消费频次显著高于另两地区(P0.017)。三地血浆PC中主要n-3多不饱和脂肪酸均为二十二碳六烯酸(DHA)。其百分含量分别为(3.31±0.77)%、(3.74±1.21)%和(2.44±0.63)%,徐水地区显著低于另两地区(P0.017)。DHA含量与海鱼摄入存在正相关(r=0.337,P0.05)。结论三地区孕妇血浆PC脂肪酸构成与膳食情况相关。妊娠期间从食物直接摄取n-3长链多不饱和脂肪酸可能比内源合成对维持体内DHA水平更具实际意义。
[Abstract]:Objective to investigate the dietary patterns of pregnant women in three regions of China, the contents of various fatty acids in plasma phosphatidylcholine (PC) and their relationship. Methods A total of 35 healthy pregnant women were selected from Tamsuihe Lake (Jiangsu Jurong Hu, Shandong Rizhao) and inland Xushui (Hebei Xushui), and 35 healthy pregnant women were selected from each region. In the second trimester of pregnancy, the dietary frequency and edible oil consumption were investigated by questionnaire, and the contents of various fatty acids in plasma PC were detected by gas chromatography in the third trimester of pregnancy. Results the frequency of sea fish consumption in sunshine pregnant women was significantly higher than that in other two areas (P 0.017). The main n-3 polyunsaturated fatty acids in plasma PC were 22 carbohexaenoic acid DHAA. The percentage content of P0.017 + DHA was 3.31 卤0.77% and 2.44 卤0.63%, respectively. There was a positive correlation between the content of P0.017, DHA and the intake of marine fish in Xushui area. Conclusion the composition of PC fatty acids in plasma of pregnant women in the three areas is related to the diet. Direct intake of n-3 long chain polyunsaturated fatty acids from food during pregnancy may be more important than endogenous synthesis in maintaining DHA levels in vivo.
【作者单位】：中国疾病预防控制中心营养与健康所;
【基金】：欧盟第六科技框架项目(No.016249-2)
【分类号】：R153.1

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