职业性汞中毒患者心身症状的调查研究
发布时间：2018-08-09 14:39
【摘要】：研究目的 我国作为制造业大国,近年来,伴随着社会经济迅速发展,但由于经济水平的限制,乡镇、个私企业的兴起,新工种、新行业、新毒物的出现,以及职业性有害因素的转嫁等问题的存在,职业卫生仍不容忽视。本文通过对职业性汞中毒患者心身症状的调查研究,认识生产过程中存在的职业性有害因素对劳动者健康的不良影响,为今后综合治疗职业中毒患者,提高疗效,提供相关参考。 资料来源与方法 以符合中华人民共和国卫生部颁发的职业性汞中毒诊断标准(GBZ89-2007诊断标准的职业性汞中毒患者作为研究对象,同期企业健康体检的志愿者为对照组。采用问卷调查方法,调查患者心理症状(症状自评量表SCL90)、睡眠质量(Pittsburgh睡眠质量指数量表PSQI)、焦虑积分(焦虑自评量表SAS)和抑郁积分(抑郁自评量表SDS)。比较分析两组的睡眠情况和焦虑抑郁情况；根据SAS、 SDS积分对职业性汞中毒组分组,并相互比较以及与对照组比较,分析各组的睡眠情况。 统计学分析 用SPSS13.0软件进行数据处理,实验所得数据以平均值土标准差表示,采用Fisher精确概率法及独立样本T检验对数据进行分析,P0.05时,认为有统计学意义。 结果： 1、一般资料：实验组,共145例,男63例,女82例,年龄22±52.58岁,工龄2.0+1.54年；对照组,59例,男28例,女31例,年龄234±2.35岁,工龄2.34±1.9年。 2、职业性汞中毒患者心理健康状况评价：实验组患者的躯体化、抑郁、焦虑、恐惧症状与对照组比较差异有显著性意义(p0.05),提示实验组伴有心理躯体症状。 3、职业性汞中毒患者焦虑抑郁评价：实验组SAS粗分29.43士15.24,SAS40分阳性率12.41%(18/145例),同比对照组SAS粗分26.10土11.55,SAS40分阳性率3.39%(2/59例)差异均有显著性意义(p0.05)。实验组SDS粗分31.29士13.32,同比对照组SDS粗分26.51士13.91差异有显著性意义(p0.05),实验组SDS40分阳性率3.39%(10/145例),同比对照组SDS40分阳性率56.90%(4/59例),差异无显著性意义(P0.05)。表明职业性汞中毒患者存在情绪障碍,且焦虑情绪更为突出。 4、职业性汞中毒患者的睡眠情况：实验组在睡眠质量、睡眠障碍和日间功能障碍3个因子以及PsQI,总分与对照组比较差异有显著性意义(p0.05),而入睡时间、睡眠时间、睡眠效率和催眠药物4个因子与对照组比较差异无显著性意义(p0.05)。表明职业性汞中毒患者较对照组存在部分因子的睡眠异常。 5、焦虑抑郁状态对职业性汞中毒患者睡眠影响分析：125例无焦虑抑郁的职业性汞中毒患者与对照组比较在睡眠质量、睡眠障碍、日间功能障碍3个因子和PSQI,总分有差异(p0.05),而入睡时间、睡眠时间、睡眠效率、催眠药物4个因子与对照组比较无差异(p0.05)。20例伴焦虑抑郁的职业性汞中毒患者与对照组比较,在睡眠质量、入睡时间、睡眠效率、睡眠障碍、睡眠时间、日间功能障碍6个因子和PSQI,总分有差异(p0.05)。只有催眠药物无差异(p0.05)。伴焦虑抑郁的职业性汞中毒患者与无焦虑抑郁的职业性汞中毒患者比较睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能障碍、催眠药物所有7个因子和PSQI,总分,均有差异(p0.05)。 结论： 1.职业性汞中毒患者存在焦虑抑郁等情绪障碍。 2.职业性汞中毒患者存在睡眠异常,主要表现在睡眠质量、睡眠障碍、日间功能障碍3个因子和PSQI.总分异常。 3.焦虑抑郁情绪障碍会加重职业性汞中毒患者的睡眠异常。
[Abstract]:research objective
As a big manufacturing country, in recent years, with the rapid development of social and economic development, the occupational health students can not be ignored because of the limitation of the economic level, the rise of township and township enterprises, the emergence of new industry, new industry, new poison, and the transfer of occupational harmful factors. The investigation of the symptoms to understand the adverse effects of occupational harmful factors on the health of the workers in the process of production, and to provide some reference for the future comprehensive treatment of occupational poisoning patients and the improvement of the curative effect.
Sources and methods of data
In accordance with the occupational mercury poisoning diagnostic criteria of occupational mercury poisoning (GBZ89-2007 diagnostic criteria) issued by the Ministry of health of the People's Republic of China as the research object, the volunteers of the medical examination in the same period were used as the control group. The psychological symptoms (symptom checklist SCL90) and sleep quality (Pittsburgh sleep) were investigated by questionnaire. Sleep quality index (PSQI), anxiety score (anxiety scale SAS) and depression score (SDS). The sleep conditions and anxiety and depression of the two groups were compared and analyzed. According to SAS, SDS scores were divided into groups of occupational mercury poisoning groups, and compared with the control group, the sleep conditions of each group were analyzed.
Statistical analysis
SPSS13.0 software is used for data processing. The experimental data are expressed with average soil standard deviation. The data are analyzed by Fisher precision probability method and independent sample T test. P0.05 is considered to have statistical significance.
Result:
1, general data: the experimental group, a total of 145 cases, 63 men, 82 women, age 22 + 52.58 years old, 2.0+1.54 years, the control group, 59 cases, 28 men, 31 cases, age 234 + 2.35 years, age 2.34 + 1.9 years.
2, evaluation of mental health status of patients with occupational mercury poisoning: the differences of somatization, depression, anxiety and fear in the experimental group were significantly different from those in the control group (P0.05), suggesting that the experimental group was accompanied by psychosomatic symptoms.
3, the evaluation of anxiety and depression in patients with occupational mercury poisoning: the SAS crude score of the experimental group was 29.43 and 15.24, the positive rate of SAS40 was 12.41% (18/145 cases), the SAS crude score of the control group was 26.10 soil 11.55, the difference of SAS40 positive rate 3.39% (2/59 cases) was significant (P0.05). The experimental group SDS crude score was 31.29 13.32, and the difference of SDS coarse 26.51 of the control group was significantly different from the same period of the same period. The positive rate of SDS40 in the experimental group (P0.05) was 3.39% (10/145 cases), and the positive rate of SDS40 in the control group was 56.90% (4/59 case), the difference was not significant (P0.05). It showed that the occupational mercury poisoning patients had emotional disorder and the anxiety was more prominent.
4, the sleep condition of the patients with occupational mercury poisoning: the 3 factors of sleep quality, sleep disorder and daytime dysfunction and the total score of PsQI in the experimental group were significantly different from those in the control group (P0.05), but there was no significant difference between 4 factors of sleep time, sleep time, sleep efficiency and hypnotic drugs (P0.05). The patients with occupational mercury poisoning had abnormal sleep with some factors compared with the control group.
5, analysis of the effects of anxiety and depression on the sleep of patients with occupational mercury poisoning: 125 patients with occupational mercury poisoning without anxiety and depression were compared with the control group in sleep quality, sleep disorder, day dysfunction 3 factors and PSQI, total score difference (P0.05), while sleep time, sleep time, sleep efficiency, hypnotic drug 4 factors and control groups Compared with the control group, there were 6 factors in sleep quality, sleep time, sleep efficiency, sleep disorder, sleep time, and PSQI, and the total scores were different (P0.05) in sleep quality, sleep time, sleep time, and PSQI (P0.05). There was no difference in hypnotics (P0.05). Patients with occupational mercury poisoning associated with anxiety and depression were no more than those in the control group. Anxiety and depression of occupational mercury poisoning patients compared sleep quality, sleep time, sleep time, sleep efficiency, sleep disorders, daytime dysfunction, hypnotic drugs all 7 factors and PSQI, total score, there are differences (P0.05).
Conclusion:
1. Occupational mercury poisoning patients have emotional disorders such as anxiety and depression.
2. Occupational mercury poisoning patients have abnormal sleep, mainly manifested in sleep quality, sleep disorders, day dysfunction three factors and PSQI. total score abnormalities.
3. Anxiety and depression may aggravate the sleep disorder of occupational mercury poisoning patients.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R135
本文编号：2174398
[Abstract]:research objective
As a big manufacturing country, in recent years, with the rapid development of social and economic development, the occupational health students can not be ignored because of the limitation of the economic level, the rise of township and township enterprises, the emergence of new industry, new industry, new poison, and the transfer of occupational harmful factors. The investigation of the symptoms to understand the adverse effects of occupational harmful factors on the health of the workers in the process of production, and to provide some reference for the future comprehensive treatment of occupational poisoning patients and the improvement of the curative effect.
Sources and methods of data
In accordance with the occupational mercury poisoning diagnostic criteria of occupational mercury poisoning (GBZ89-2007 diagnostic criteria) issued by the Ministry of health of the People's Republic of China as the research object, the volunteers of the medical examination in the same period were used as the control group. The psychological symptoms (symptom checklist SCL90) and sleep quality (Pittsburgh sleep) were investigated by questionnaire. Sleep quality index (PSQI), anxiety score (anxiety scale SAS) and depression score (SDS). The sleep conditions and anxiety and depression of the two groups were compared and analyzed. According to SAS, SDS scores were divided into groups of occupational mercury poisoning groups, and compared with the control group, the sleep conditions of each group were analyzed.
Statistical analysis
SPSS13.0 software is used for data processing. The experimental data are expressed with average soil standard deviation. The data are analyzed by Fisher precision probability method and independent sample T test. P0.05 is considered to have statistical significance.
Result:
1, general data: the experimental group, a total of 145 cases, 63 men, 82 women, age 22 + 52.58 years old, 2.0+1.54 years, the control group, 59 cases, 28 men, 31 cases, age 234 + 2.35 years, age 2.34 + 1.9 years.
2, evaluation of mental health status of patients with occupational mercury poisoning: the differences of somatization, depression, anxiety and fear in the experimental group were significantly different from those in the control group (P0.05), suggesting that the experimental group was accompanied by psychosomatic symptoms.
3, the evaluation of anxiety and depression in patients with occupational mercury poisoning: the SAS crude score of the experimental group was 29.43 and 15.24, the positive rate of SAS40 was 12.41% (18/145 cases), the SAS crude score of the control group was 26.10 soil 11.55, the difference of SAS40 positive rate 3.39% (2/59 cases) was significant (P0.05). The experimental group SDS crude score was 31.29 13.32, and the difference of SDS coarse 26.51 of the control group was significantly different from the same period of the same period. The positive rate of SDS40 in the experimental group (P0.05) was 3.39% (10/145 cases), and the positive rate of SDS40 in the control group was 56.90% (4/59 case), the difference was not significant (P0.05). It showed that the occupational mercury poisoning patients had emotional disorder and the anxiety was more prominent.
4, the sleep condition of the patients with occupational mercury poisoning: the 3 factors of sleep quality, sleep disorder and daytime dysfunction and the total score of PsQI in the experimental group were significantly different from those in the control group (P0.05), but there was no significant difference between 4 factors of sleep time, sleep time, sleep efficiency and hypnotic drugs (P0.05). The patients with occupational mercury poisoning had abnormal sleep with some factors compared with the control group.
5, analysis of the effects of anxiety and depression on the sleep of patients with occupational mercury poisoning: 125 patients with occupational mercury poisoning without anxiety and depression were compared with the control group in sleep quality, sleep disorder, day dysfunction 3 factors and PSQI, total score difference (P0.05), while sleep time, sleep time, sleep efficiency, hypnotic drug 4 factors and control groups Compared with the control group, there were 6 factors in sleep quality, sleep time, sleep efficiency, sleep disorder, sleep time, and PSQI, and the total scores were different (P0.05) in sleep quality, sleep time, sleep time, and PSQI (P0.05). There was no difference in hypnotics (P0.05). Patients with occupational mercury poisoning associated with anxiety and depression were no more than those in the control group. Anxiety and depression of occupational mercury poisoning patients compared sleep quality, sleep time, sleep time, sleep efficiency, sleep disorders, daytime dysfunction, hypnotic drugs all 7 factors and PSQI, total score, there are differences (P0.05).
Conclusion:
1. Occupational mercury poisoning patients have emotional disorders such as anxiety and depression.
2. Occupational mercury poisoning patients have abnormal sleep, mainly manifested in sleep quality, sleep disorders, day dysfunction three factors and PSQI. total score abnormalities.
3. Anxiety and depression may aggravate the sleep disorder of occupational mercury poisoning patients.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R135
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