2011-2013年海南省疑似预防接种异常反应监测分析

发布时间：2018-08-17 16:55

【摘要】：目的分析海南省疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)发生特征,评价AEFI信息管理系统运转质量和疫苗安全性,指导预防接种工作。方法通过全国AEFI信息管理系统收集海南省2011-2013年AEFI监测数据,采用描述流行病学方法进行分析。结果海南省2011-2013年共报告AEFI 3 860例,报告发生率为3.14/万剂。AEFI报告市县覆盖率100.00%,48 h及时报告率96.35%,48 h及时调查率99.44%。AEFI分类一般反应占73.91%,异常反应占21.99%,偶合症3.89%,其他反应占0.21%,异常反应主要以过敏性皮疹、卡介苗淋巴结炎和血管性水肿为主。全年均有AEFI报告,5月和11月报告AEFI最多,男女性别比例为1.60∶1,3岁内儿童报告最多。AEFI转归情况:治愈占99.80%,后遗症4例,死亡4例。结论海南省AEFI监测敏感性较高;AEFI主要以一过性反应为主,目前所使用的疫苗是安全的;需加强对基层接种人员接种技术培训。
[Abstract]:Objective to analyze the characteristics of (Adverse Events Following immune response (Adverse Events Following) in Hainan Province, to evaluate the quality of AEFI information management system and the safety of vaccine, and to guide vaccination. Methods the data of AEFI surveillance in Hainan Province from 2011 to 2013 were collected by AEFI information management system and analyzed by descriptive epidemiology. Results A total of 3 860 cases of AEFI were reported in Hainan Province from 2011 to 2013. The reported incidence rate was 3.14 / 10 000 doses. AEFI reported the city and county coverage rate 100.00000 hours and 48 h timely report rate 96.3535 and 48 hours timely investigation rate. 99.44%.AEFI classification general reaction accounted for 73.91%, abnormal reaction accounted for 21.99%, incidental disease 3.89g, other reaction 0.21. The abnormal reaction was mainly allergic rash. BCG lymphadenitis and vascular edema were predominant. There were AEFI reports in the whole year, AEFI in May and November, and the sex ratio of male and female was 1.60: 1%. AEFI was the most. AEFI outcome: cure accounted for 99.80, sequelae 4 cases, death 4 cases. Conclusion the high sensitivity of AEFI surveillance in Hainan Province is mainly caused by transient reaction, and the vaccine used at present is safe, and it is necessary to strengthen the training of inoculation techniques for the basic level vaccinators.
【作者单位】：海南省预防控制中心;
【基金】：海南省自然科学基金项目(310176)
【分类号】：R186

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