甲状腺良恶性病变的双源CT能谱特征分析

发布时间：2018-01-14 07:26

本文关键词：甲状腺良恶性病变的双源CT能谱特征分析　出处：《中国临床研究》2016年10期 　论文类型：期刊论文

【摘要】：目的分析甲状腺癌及结节性甲状腺肿的双源CT能谱曲线及碘图特点,为甲状腺良恶性病变的鉴别诊断提供依据。方法回顾性分析2014年1月至2015年8月进行双源CT检查,并经临床手术病理确诊甲状腺癌及结节性甲状腺肿患者55例的临床及影像资料,其中甲状腺癌20例,结节性甲状腺肿35例。所有患者均行西门子双源炫速CT双能量平扫、动脉期及静脉期扫描,应用liver VNC和Monoenergetic软件得到病变区域碘浓度、碘图及能谱曲线,比较甲状腺癌与结节性甲状腺肿患者的能谱曲线斜率、碘浓度。结果平扫甲状腺癌患者的能谱曲线斜率及碘浓度低于结节性甲状腺肿患者,差异均有统计学意义(P均0.01);动脉期甲状腺癌患者的能谱曲线斜率、甲状腺与颈总动脉碘浓度比值均低于结节性甲状腺肿患者,差异均有统计学意义(P均0.01);静脉期甲状腺癌患者的能谱曲线斜率、甲状腺与颈总动脉碘浓度比值与结节性甲状腺肿患者比较,差异均无统计学意义(P均0.05)。结论双源CT双能量定量参数测定可以对甲状腺良恶性病变的鉴别诊断提供依据,提高诊断准确率。
[Abstract]:Objective to analyze the thyroid carcinoma and nodular goiter by dual source CT spectral curve and iodine maps provide the basis for the characteristics of the differential diagnosis of benign and malignant thyroid lesions. Methods: DUALSOURCE CT analysis from January 2014 to August 2015, and the clinical and imaging data of 55 cases of clinical pathological diagnosis surgery of thyroid carcinoma and nodular goiter patients among them, 20 cases of thyroid carcinoma, 35 cases of nodular goiter. All patients underwent SIEMENS Hyun speed dual source dual energy CT scan, arterial phase and venous phase scan, using liver VNC and Monoenergetic software from the lesion areas of iodine concentration, iodine maps and energy spectrum curve, energy spectrum curve slope comparison of thyroid carcinoma and nodular. Goiter in iodine concentration. The flat spectrum curve slope and the iodine concentration is lower than that of the patients with nodular goiter and thyroid cancer patients, the differences were statistically significant (P 0.01); Energy spectrum curve slope of thyroid cancer patients with arterial phase, thyroid iodine concentration and carotid artery was significantly lower than that of nodular goiter patients, the differences were statistically significant (P < 0.01); energy spectrum curve slope of thyroid cancer patients with venous phase, compared with the common carotid artery of thyroid iodine concentration and the ratio of patients with nodular goiter, there were no significant differences (P < 0.05). Conclusion dual energy CT quantitative parameters in differential diagnosis of benign and malignant thyroid lesions provide the basis to improve the accuracy of diagnosis.

【作者单位】：新疆医科大学第五附属医院影像中心;南京江北人民医院介入科;
【基金】：新疆维吾尔自治区自然科学基金(2014211C126) 南京市医学科技发展项目(YKK14223)
【分类号】：R736.1;R730.44;R581
【正文快照】： 甲状腺占位是临床常见疾病,3%~8%的成年人触诊或影像学检查可发现有甲状腺结节[1]。术前准确判断甲状腺占位性质,对手术方案的制定和患者的预后具有重要意义。影像学检查是主要诊断方法,但特异性不高[2]。双源CT双能量扫描可同时获得能谱曲线及碘基图像,通过计算能获得甲状腺

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