AECOPD患者64层MSCT肺容积成像与肺功能测定的相关性研究

发布时间：2018-01-15 01:28

本文关键词：AECOPD患者64层MSCT肺容积成像与肺功能测定的相关性研究　出处：《临床肺科杂志》2016年10期 　论文类型：期刊论文

【摘要】：目的分析64层螺旋CT(MSCT)检测慢性阻塞性肺疾病急性加重期(AECOPD)患者肺容积指数的准确性,探讨MSCT对AECOPD患者的诊断价值,为AECOPD患者的临床诊断提供可借鉴的方法。方法选取2014年1月-2015年9月我院呼吸内科收治的AECOPD患者247例为观察组,另选取同期接受体检的健康志愿者50例为对照组,进行64层MSCT肺容积成像和常规肺功能检查(PFT),两项检查时间间隔小于3天,测定两组不同肺区的肺容积指标并与临床PFT指标进行相关性分析。结果观察组与对照组的肺功能指标存在差异,具有统计学意义(P0.05)。观察组的肺容积指标Vin、Vex、(Vin-Vex)、Vin/Vex、(VinVex)/Vin与对照组的各项肺容积指标亦存在着差异,具有统计学意义,(P0.05)。本研究中还发现,观察组MSCT肺容积指标Vex、Vex/Vin、Vin-Vex/Vin与FEV_1、FEV_1/FVC、TLC、RV/TLC之间均有相关性;Vin与FEV_1/FVC、TLC、RV/TLC之间有相关性;Vin-Vex与肺功能指标之间无相关性。结论 64排螺旋CT呼吸双相高分辨率肺容积测定指标与肺功能测定指标具有良好相关性,对诊断AECOPD有预测意义。
[Abstract]:Objective to analyze the accuracy of 64-slice spiral CT MSCT in detecting pulmonary volume index in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). To investigate the diagnostic value of MSCT in AECOPD patients. Methods from January 2014 to September 2015, 247 patients with AECOPD were selected as the observation group. In addition, 50 healthy volunteers who received physical examination in the same period were selected as control group. 64-layer MSCT pulmonary volume imaging and routine pulmonary function examination were performed. The interval between the two examinations was less than 3 days. The lung volume indexes of different lung regions in two groups were measured and the correlation analysis with clinical PFT indexes was carried out. Results there were differences in pulmonary function indexes between the observation group and the control group. The lung volume index of the observation group was Vinovexus Vexanum Vin-Vexus Vex / Vex. There was also significant difference in lung volume between VinVexin / Vin and the control group (P 0.05). It was also found in this study. In the observation group, there was a correlation between VX / VX / VX / VIN and FEV1FEV1 / FVCV / TLCRV / TLC / TLC; There was a correlation between Vin and FEVS 1 / FVC / TLC. There was no correlation between Vin-Vex and pulmonary function index. Conclusion 64-slice spiral CT has a good correlation with lung function index and respiratory biphasic high-resolution pulmonary volume measurement index. It can predict the diagnosis of AECOPD.
【作者单位】：上海市嘉定区中心医院放射科;上海市嘉定区中心医院呼吸内科;
【基金】：上海市嘉定区科委科研项目(No 2013-KW-11)
【分类号】：R563.9;R816.41
【正文快照】： 慢性阻塞性肺疾病是一种慢性疾病,它的病理基础是终末细支气管远端气腔永久性扩大,伴有肺泡壁破坏及肺弹性收缩过度和通气障碍。临床慢阻肺疾病诊断的金标准是肺功能检测(PFT)[1]。慢阻肺规范化治疗有赖于肺功能分级。AECOPD患者由于发病时症状较重,许多患者不能耐受肺功能检

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