分形维数在CT腰椎松质骨图像中应用的研究

发布时间：2018-01-28 04:44

本文关键词： 骨质疏松症 CT 分形维数　出处：《同济大学学报(医学版)》2016年03期 　论文类型：期刊论文

【摘要】：目的探讨分形维数(fractal dimension,FD)在腰椎CT中对松质骨微结构量化的应用价值。方法回顾性分析2012年12月至2015年9月,因腰痛来本院就诊并行腰椎CT检查的中青年男性患者115例,分为两组:A组,28~31岁,61例;B组,38~41岁,54例。入组者均无腰椎退行性变,使用imagej分析腰4椎体松质骨区域图像,量化灰度纹理特征。检验FD值在两组间的差异并行ROC曲线分析。结果 A组腰椎松质骨的FD值为1.463±0.056,B组腰椎松质骨的FD值为1.418±0.038,两组间的差异有统计学意义(P=0.001)。经ROC曲线分析,判断FD最佳临近点为1.423,此时诊断的灵敏度为75.4%,特异度为55.6%。结论采用分形维数分析腰椎松质骨CT图像,提取灰度纹理信息,可量化一定轻微退变程度的骨微结构。
[Abstract]:Objective to investigate fractal dimension and fractal dimension. Methods from December 2012 to September 2015, the value of FDD in quantifying the microstructure of cancellous bone was analyzed retrospectively. 115 young and middle-aged male patients who came to our hospital for low back pain and underwent lumbar CT examination were divided into two groups: group A (n = 61), group A (n = 2831), and group A (n = 61). Group B (n = 54) was 41 years old. There were no degenerative lumbar vertebrae in group B. imagej was used to analyze the cancellous bone area of lumbar 4 vertebrae. The difference of FD value between the two groups and ROC curve analysis were examined. Results the FD value of lumbar cancellous bone in group A was 1.463 卤0.056. The FD value of lumbar cancellous bone in group B was 1.418 卤0.038, and the difference between the two groups was statistically significant (P < 0.01). The results were analyzed by ROC curve. The best approach point for FD is 1.423, the diagnostic sensitivity is 75.4 and the specificity is 55.6. Conclusion Fractal dimension is used to analyze CT images of lumbar cancellous bone, and gray-scale texture information is extracted. The bone structure of a certain degree of slight degeneration can be quantified.
【作者单位】：南京医科大学附属无锡人民医院医学影像科;
【基金】：国家自然科学基金面上项目(81271629)
【分类号】：R580;R816.8
【正文快照】： 骨质疏松症是一种以骨量低下,骨微结构破坏,导致骨脆性增加,易发生骨折为特征的全身性骨病[1]。双能X线吸收法(DXA)是学术界公认的骨密度检查方法,但其不能有效评估骨微结构的变化[1-2]。腰椎及腰椎间盘CT扫描是患者因腰痛就诊比较普遍的检查。临床CT诊断中,只观察腰椎骨赘、

【相似文献】