低剂量螺旋CT在肺癌及乳腺癌双筛中的临床价值初探

发布时间：2018-01-30 09:06

本文关键词： 体层摄影术螺旋计算机放射摄影术超声检查肺肿瘤乳腺肿瘤筛查　出处：《实用医学影像杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的探讨低剂量螺旋CT(LDCT)对女性胸部体检者肺癌、乳腺癌-查双筛的临床价值。方法2 388名无症状女性行胸部LDCT体检,另外4 876名无症状女性行数字化X线摄影(DR)体检,比较两者对肺部病变与肺癌的检出率;上述2 388名女性同时行乳腺超声(US)检查,比较LDCT与US对乳腺病变与乳腺癌的检出率。结果 LDCT组检出肺部病变792例,检出率为33.17%,检出经病理或临床证实的肺癌27例,肺癌检出率为1.13%;DR组检出肺部病变939例,检出率为19.26%,检出经病理或临床证实的肺癌16例,肺癌检出率为0.33%;LDCT对肺部病变与肺癌的检出率均高于DR,差异有统计学意义(P均0.01)。LDCT组检出乳腺病变190例,检出率为7.96%,检出经病理或临床证实的乳腺癌26例,检出率为1.09%;US检出乳腺病变203例,检出率为8.50%,检出经病理或临床证实的乳腺癌19例,检出率为0.79%;LDCT对乳腺病变的检出率与US相若(P=0.066),乳腺癌的检出率高于US,差异有统计学意义(P=0.039)。结论 LDCT对肺癌的筛查检出率分别优于DR,乳腺癌的检测率接近US,对胸部LDCT女性体检者行肺癌与乳腺癌-查双筛有利于提高2种癌的检出率,可以降低检查成本,值得推广应用。
[Abstract]:Objective to investigate the clinical value of low dose spiral CTT in the diagnosis of lung cancer and breast cancer in female patients with chest examination. Methods LDCT examination was performed in 2 388 asymptomatic women. In addition, 4 876 asymptomatic women were examined by digital radiography (DRN) to compare the detection rates of lung lesions and lung cancer. The detection rates of breast lesions and breast cancer were compared between LDCT and US. Results 792 cases of pulmonary lesions were detected in LDCT group. The detectable rate of lung cancer was 33.17. 27 cases of lung cancer confirmed by pathology or clinic were detected, and the positive rate of lung cancer was 1.13%. In Dr group, 939 cases of pulmonary lesions were detected, the detection rate was 19.26, and 16 cases of lung cancer confirmed by pathology or clinic were detected, the detection rate of lung cancer was 0.33%. The detection rate of LDCT for lung lesions and lung cancer was higher than that for lung cancer, and the difference was statistically significant (P < 0.01). The detection rate of breast lesions was 7.96% in LDCT group. 26 cases of breast cancer confirmed by pathology or clinic were detected, the detection rate was 1.09%. 203 cases of breast lesions were detected by US, the detection rate was 8.50%, and 19 cases of breast cancer confirmed by pathology or clinic were detected, the detection rate was 0.79%. The detection rate of breast lesions by LDCT was similar to that of US. The detection rate of breast cancer was higher than that of US. Conclusion the detection rate of LDCT for lung cancer is better than that of DRR, and the detection rate of breast cancer is close to that of US. The double screening of lung cancer and breast cancer in women with LDCT can improve the detection rate of two kinds of cancer and reduce the cost of examination, so it is worth popularizing and applying.
【作者单位】：中山大学附属第五医院放射科;中山大学附属第五医院超声科;
【分类号】：R734.2;R737.9;R730.44;R445.1
【正文快照】： 肺癌与乳腺癌是当前对人类威胁极大的两类恶性肿瘤。肺癌病死率常年高居男性首位,女性第二位。而乳腺癌的发病率呈逐年上升趋势[1],尤其是京、津、沪等大城市,已位居女性恶性肿瘤发病率之首[2]。乳腺癌的患病率呈现逐年上升的趋势,且发病年龄趋向年轻化[3]。临床研究表明,早期

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