宽体探测器全肾脏CT灌注扫描持续时间对灌注参数的影响

发布时间：2018-02-10 18:51

本文关键词： 肾体层摄影术 X线计算机血管造影术灌注成像肾血流量有效　出处：《中国医学影像学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨应用Revolution CT行轴位全肾脏灌注成像,扫描持续时间对灌注参数值的影响。资料与方法前瞻性研究双侧肾脏无器质性病变患者42例,按照灌注扫描持续时间将患者分为短灌注组(A组)和长灌注组(B组)。使用Revolution CT机轴扫模式进行灌注扫描,探测器宽度16 cm。A组采用管电压80 k Vp,管电流200 m A,每2 s(曝光0.5 s,间隔1.5 s)采集1次,共采集25期图像,总灌注时间50 s。B组采用管电压120 k Vp,管电流55 m A,采用间隔采集,每次采集时间均为2 s(曝光0.5 s,间隔1.5 s),最终获得23期图像,总灌注时间为594 s。使用CT Perfusion4D灌注软件包进行后处理,选择右侧肾门水平腹主动脉为输入动脉,得到灌注参数图。分别比较两组组内双侧肾脏皮髓质间各灌注参数及两组间肾脏皮髓质各灌注参数间的差异。记录CT容积剂量指数(CTDIvol)及剂量-长度乘积(DLP),计算并比较有效剂量(ED)。结果两组组内双侧肾脏各灌注参数对比差异无统计学意义(P0.05)。两组间肾脏皮、髓质的血容量、达峰时间及表面通透性差异均有统计学意义(P0.05)。两组间肾脏髓质的平均通过时间差异有统计学意义(P0.05),而皮、髓质的血流量和皮质的平均通过时间差异无统计学意义(P0.05)。A组灌注扫描、髓质期及排泄期的总ED平均为(23.10±4.39)m Sv;B组为(23.19±0.00)m Sv,差异无统计学意义(P0.05)。结论全肾脏灌注成像中,短灌注时间与长灌注时间的灌注参数具有明显差异,因此需根据不同临床需要设计扫描时间。
[Abstract]:Objective to investigate the effect of Revolution CT on the perfusion parameters of renal perfusion imaging. Materials and methods A prospective study of 42 patients with bilateral renal non-organic lesions was carried out. According to the duration of perfusion scan, the patients were divided into two groups: group A (short perfusion group) and group B (long perfusion group). Perfusion scanning was performed using Revolution CT axial scan mode. The detector width of 16 cm.A group was collected once every 2 s (exposure 0.5 s, interval 1.5 s) with a tube voltage of 80 kV / p and a current of 200 Ma. The total perfusion time of group B was 50 s. The total perfusion time of group B was 120kVp, the current of the tube was 55mA, and the interval acquisition was used. Each acquisition time was 2 s (exposure 0.5 s, interval 1.5 s-1), and 23 phase images were obtained, the total perfusion time was 594s. Ct Perfusion4D perfusion software package was used for post-processing, and the right lateral abdominal aorta was selected as the input artery. The perfusion parameters were obtained. The perfusion parameters between the bilateral renal medulla and the renal medullary perfusion parameters between the two groups were compared, respectively. The CT volume dose index (CTDIvoll) and the dose length product (DLPU) were recorded and calculated. Results there was no significant difference in renal perfusion parameters between the two groups (P 0.05). There were significant differences in blood volume, peak time and surface permeability between the two groups (P 0.05). There was no significant difference in the blood flow of medulla and the mean transit time of cortex. The total Ed in the medullary phase and excretory phase was 23.10 卤4.39mSv-B, which was 23.19 卤0.005mSv.Conclusion in the whole renal perfusion imaging, there is no significant difference in the blood flow and the mean transit time of the cortex (P 0.05). Conclusion in the whole renal perfusion imaging, the total Ed in the medullary phase and excretion phase is 23.19 卤0.00m Sv, respectively. The perfusion parameters of short perfusion time and long perfusion time are obviously different, so scan time should be designed according to different clinical needs.
【作者单位】：大连医科大学附属第一医院放射科;
【分类号】：R816.7

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